Question 1

The interaction of many different protein factors to stimulate or repress transcription is called:

Accepted Answer

A)  combinatorial control. 
B)  synergy. 
C)  the hypomethylation effect. 
D)  All of the above. 
E)  None of the above. 
A)  combinatorial control. 
B)  synergy. 
C)  the hypomethylation effect. 
D)  All of the above. 
E)  None of the above. A

Question 2

Why are steroid hormone receptors excellent drug therapy targets?

Accepted Answer

These receptors influence many genes and pathways. By designing a substrate of the hormone (antagonist), it is possible to have drug binding to the receptor without triggering the exact same reaction as the native hormone does.

Question 3

What are induced pluripotent stem cells?

Accepted Answer

Pluripotent stem cells have the ability to differentiate into different cell types, depending on signals from the environment. There are four genes that encode transcription factors, which, when introduced into mature fibroblast skin cells, will cause them to return to a pluripotent stem cell state. Thus, pluripotency has been induced.

Question 4

RNA polymerase I is located in the ________________.

Accepted Answer

The answer of RNA polymerase I is located in the...

Question 5

Enhancer sites are often located:

Accepted Answer

A)  near the poly(
A)  tail site. 
B)  within introns. 
C)  at a distance from the transcription start site. 
D)  All of the above. 
E)  None of the above. 
A)  near the poly(
A)  tail site. 
B)  within introns. 
C)  at a distance from the transcription start site. 
D)  All of the above. 
E)  None of the above.

Question 6

A key reaction in gene repression is the deacetylation of this/these amino acids in histones:

Accepted Answer

A)  serine. 
B)  threonine. 
C)  arginine. 
D)  lysine. 
E)  All of the above. 
A)  serine. 
B)  threonine. 
C)  arginine. 
D)  lysine. 
E)  All of the above.

Question 7

The carboxyl-terminal domain of RNA polymerase II is phosphorylated on ________________ residues.

Accepted Answer

The answer of The carboxyl-terminal domain of RNA polymerase II...

Question 8

What are the three most common cis-acting elements for genes transcribed by RNA polymerase II?

Accepted Answer

The most common is called the

Question 9

What additional complexities exist between gene expression in eukaryotes but not in prokaryotes?

Accepted Answer

Regulation of transcription of a gene in

Question 10

Eukaryotic RNA polymerases differ in their sensitivity to the mushroom toxin _____________.

Accepted Answer

The answer of Eukaryotic RNA polymerases differ in their sensitivity...

Question 11

What benefit does combinatorial control give to multicellular organisms?

Accepted Answer

Combinatorial control means th

Question 12

Use the following to answer questions 
Choose the correct answer from the list below. Not all of the answers will be used.
-A(n) ______________ is a region of a protein that regulates transcription by interacting with the acetylated lysine of histones.

Accepted Answer

A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger 
A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger

Question 13

The repeating unit formed by the DNA wrapping around the histone core is called a(n) ________________.

Accepted Answer

The answer of The repeating unit formed by the DNA...

Question 14

Use the following to answer questions 
Choose the correct answer from the list below. Not all of the answers will be used.
-Binding sites in DNA for specific regulatory proteins are called ______________.

Accepted Answer

A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger 
A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger

Question 15

Use the following to answer questions 
Choose the correct answer from the list below. Not all of the answers will be used.
-In eukaryotes, transcription is initiated by the binding of the transcription factor to the ______________.

Accepted Answer

A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger 
A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger

Question 16

________________ genes are continuously expressed rather than regulated.

Accepted Answer

The answer of ________________ genes are continuously expressed rather than...

Question 17

Why must gene regulation be more complicated in eukaryotic cells when compared to prokaryotic cells?

Accepted Answer

Eukaryotic cells do not contain operons

Question 18

When phosphorylated, the carboxyl-terminal domain of RNA polymerase II:

Accepted Answer

A)  is insensitive to α-amanitin. 
B)  enhances transcription. 
C)  recruits other factors. 
D)  A and C. 
E)  B and C. 
A)  is insensitive to α-amanitin. 
B)  enhances transcription. 
C)  recruits other factors. 
D)  A and C. 
E)  B and C.

Question 19

Use the following to answer questions 
Choose the correct answer from the list below. Not all of the answers will be used.
-Molecules that bind to a receptor and trigger a signaling pathway are called ______________.

Accepted Answer

A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger 
A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger

Question 20

Use the following to answer questions 
Choose the correct answer from the list below. Not all of the answers will be used.
-The enzyme that removes the acetyl group for a lysine of a histone is called ______________.

Accepted Answer

A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger 
A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger

Exam 37: Gene Expression in Eukaryotes

The interaction of many different protein factors to stimulate or repress transcription is called:

Why are steroid hormone receptors excellent drug therapy targets?

What are induced pluripotent stem cells?

RNA polymerase I is located in the ________________.

Enhancer sites are often located:

A key reaction in gene repression is the deacetylation of this/these amino acids in histones:

The carboxyl-terminal domain of RNA polymerase II is phosphorylated on ________________ residues.

What are the three most common cis-acting elements for genes transcribed by RNA polymerase II?

What additional complexities exist between gene expression in eukaryotes but not in prokaryotes?

Eukaryotic RNA polymerases differ in their sensitivity to the mushroom toxin _____________.

What benefit does combinatorial control give to multicellular organisms?

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -A(n) ______________ is a region of a protein that regulates transcription by interacting with the acetylated lysine of histones.

The repeating unit formed by the DNA wrapping around the histone core is called a(n) ________________.

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -Binding sites in DNA for specific regulatory proteins are called ______________.

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -In eukaryotes, transcription is initiated by the binding of the transcription factor to the ______________.

________________ genes are continuously expressed rather than regulated.

Why must gene regulation be more complicated in eukaryotic cells when compared to prokaryotic cells?

When phosphorylated, the carboxyl-terminal domain of RNA polymerase II:

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -Molecules that bind to a receptor and trigger a signaling pathway are called ______________.

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -The enzyme that removes the acetyl group for a lysine of a histone is called ______________.

Biochemistry and the Unity of Life

Water, Weak Bonds, and the Generation of Order Out of Chaos

Amino Acids

Protein Three-Dimensional Structure

Techniques in Protein Biochemistry

Basic Concepts of Enzyme Action

Kinetics and Regulation

Mechanisms and Inhibitors

Hemoglobin: an Allosteric Protein

Carbohydrates

Lipids

Membrane Structure and Function

Signal Transduction Pathways

Digestion: Turning a Meal Into Cellular Biochemicals

Metabolism: Basic Concepts and Design

Glycolysis

Gluconeogenesis

Preparation for the Cycle

Harvesting Electrons From the Cycle

The Electron Transport Chain

The Proton-Motive Force

The Light Reactions

The Calvin Cycle

Glycogen Degradation

Glycogen Synthesis

The Pentose Phosphate Pathway

Fatty Acid Degredation

Fatty Acid Synthesis

Lipid Synthesis

Amino Acid Degradation and the Urea Cycle

Amino Acids Synthesis

Nucleotide Metabolism

The Structure of Informational Macromolecules: Dna and Rna

DNA Replication

DNA Repair and Recombination

RNA Synthesis and Regulation in Prokaryotes

RNA Processing in Eukaryotes

The Genetic Code

The Mechanism of Protein Synthesis

Recombinant Dna Techniques

Filters