Question 1

Photolyase functions to:

Accepted Answer

A)  repair pyrimidine dimers. 
B)  remove damaged bases. 
C)  ligate single-strand breaks. 
D)  All of the above. 
E)  None of the above. 
A)  repair pyrimidine dimers. 
B)  remove damaged bases. 
C)  ligate single-strand breaks. 
D)  All of the above. 
E)  None of the above. A

Question 2

Describe the consequences of incorrect DNA replication or DNA damage.

Accepted Answer

The most serious consequences are cell death, cell transformation, and blockage of DNA replication. The changes in DNA can also be inherited and passed on to future generations.

Question 3

___________________ is the enzyme that converts polycyclic aromatic hydrocarbons into a reactive epoxide that alkylates the N-7 of guanine.

Accepted Answer

cytochrome P450

Question 4

The human genetic skin disease that is caused by a mutation in components of the human nucleotide-excision-repair pathway is called ___________________.

Accepted Answer

xeroderma

Question 5

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is/are involved in joining DNA molecules together.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 6

The process whereby two daughter molecules of DNA are formed by the exchange of genetic material between two parent molecules is known as:

Accepted Answer

A)  chemical modification. 
B)  recombination. 
C)  alkylation. 
D)  dimerization. 
E)  None of the above. 
A)  chemical modification. 
B)  recombination. 
C)  alkylation. 
D)  dimerization. 
E)  None of the above.

Question 7

Why is thymine used in DNA instead of uracil?

Accepted Answer

The methyl group on thymine al

Question 8

A photoreactivating enzyme is called ___________________.

Accepted Answer

The answer of A photoreactivating enzyme is called ___________________....

Question 9

What role does the protein RAD51 play in recombination?

Accepted Answer

RAD51 is a member of the ATPas

Question 10

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is/are caused by expanded trinucleotide repeats.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 11

X-rays cause damage to DNA by inducing ___________________.

Accepted Answer

single- an

Question 12

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is a rare skin disease caused by the inability to correct for UV damage to skin DNA.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 13

What does the phrase "recombination of genetic material" refer to?

Accepted Answer

It refers to the situation in

Question 14

Light-driven DNA damage results in ___________________.

Accepted Answer

The answer of Light-driven DNA damage results in ___________________....

Question 15

Damage to DNA may result in:

Accepted Answer

A)  cell death. 
B)  cell transformation. 
C)  changes in inherited sequences. 
D)  blockage of DNA replication. 
E)  All of the above. 
A)  cell death. 
B)  cell transformation. 
C)  changes in inherited sequences. 
D)  blockage of DNA replication. 
E)  All of the above.

Question 16

In E. coli, mismatch repair involves:

Accepted Answer

A)  recognition of mismatched pair by MutS. 
B)  removal of a mismatched nucleotide by DNA polymerase III. 
C)  cleavage of the backbone by MutH. 
D)  A and C 
E)  A, B, and C. 
A)  recognition of mismatched pair by MutS. 
B)  removal of a mismatched nucleotide by DNA polymerase III. 
C)  cleavage of the backbone by MutH. 
D)  A and C 
E)  A, B, and C.

Question 17

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-_______________ is the process for correcting for base-pair mismatches without excising bases.

Accepted Answer

A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase 
A) uracil 
B) DNA ligase 
C) Huntington disease 
D) Ames 
E) xeroderma pigmentosum
F)tumor-suppressor genes
G)trinucleotide repeats
H)skin carcinoma
I)mutagen
J)direct repair
K)indirect repair
L)photolyase

Question 18

Describe the Ames test.

Accepted Answer

The Ames test is a simple and sensitive

Question 19

Name the types of DNA repair, categorized in groups.

Accepted Answer

The types include di

Question 20

Tumor-suppressor genes have a dominant negative genetic trait. What does this mean?

Accepted Answer

The loss of one copy results in the expr

Exam 35: DNA Repair and Recombination

Photolyase functions to:

Describe the consequences of incorrect DNA replication or DNA damage.

___________________ is the enzyme that converts polycyclic aromatic hydrocarbons into a reactive epoxide that alkylates the N-7 of guanine.

The human genetic skin disease that is caused by a mutation in components of the human nucleotide-excision-repair pathway is called ___________________.

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is/are involved in joining DNA molecules together.

The process whereby two daughter molecules of DNA are formed by the exchange of genetic material between two parent molecules is known as:

Why is thymine used in DNA instead of uracil?

A photoreactivating enzyme is called ___________________.

What role does the protein RAD51 play in recombination?

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is/are caused by expanded trinucleotide repeats.

X-rays cause damage to DNA by inducing ___________________.

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is a rare skin disease caused by the inability to correct for UV damage to skin DNA.

What does the phrase "recombination of genetic material" refer to?

Light-driven DNA damage results in ___________________.

Damage to DNA may result in:

In E. coli, mismatch repair involves:

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is the process for correcting for base-pair mismatches without excising bases.

Describe the Ames test.

Name the types of DNA repair, categorized in groups.

Tumor-suppressor genes have a dominant negative genetic trait. What does this mean?

Biochemistry and the Unity of Life

Water, Weak Bonds, and the Generation of Order Out of Chaos

Amino Acids

Protein Three-Dimensional Structure

Techniques in Protein Biochemistry

Basic Concepts of Enzyme Action

Kinetics and Regulation

Mechanisms and Inhibitors

Hemoglobin: an Allosteric Protein

Carbohydrates

Lipids

Membrane Structure and Function

Signal Transduction Pathways

Digestion: Turning a Meal Into Cellular Biochemicals

Metabolism: Basic Concepts and Design

Glycolysis

Gluconeogenesis

Preparation for the Cycle

Harvesting Electrons From the Cycle

The Electron Transport Chain

The Proton-Motive Force

The Light Reactions

The Calvin Cycle

Glycogen Degradation

Glycogen Synthesis

The Pentose Phosphate Pathway

Fatty Acid Degredation

Fatty Acid Synthesis

Lipid Synthesis

Amino Acid Degradation and the Urea Cycle

Amino Acids Synthesis

Nucleotide Metabolism

The Structure of Informational Macromolecules: Dna and Rna

DNA Replication

RNA Synthesis and Regulation in Prokaryotes

Gene Expression in Eukaryotes

RNA Processing in Eukaryotes

The Genetic Code

The Mechanism of Protein Synthesis

Recombinant Dna Techniques

Filters