Exam 38: RNA Processing in Eukaryotes

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What role do small nucleolar ribonucleoproteins (snoRNPs) play in RNA processing?

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snoRNPs direct the extensive modification of nucleotides in pre-rRNA. These modifications occur on both ribose and based components and include methylation reactions and the formation of pseudouridine.

Noncoding regions of RNA are called:

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C

At least __________ % of all genetic diseases are caused by mutations that affect RNA splicing.

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How are introns detected for splicing?

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The small subunit of ribosomal RNA is _________________ S.

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The function of guanosine in self-splicing is:

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Choose the correct answer from the list below. Not all of the answers will be used. -______________: These small nuclear RNAs form the catalytic center of the spliceosome.

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The immediate product of RNA polymerase II is often referred to as _________________.

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RNA self-splicing demonstrates the role of RNA as a(n) _________________.

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What are the two types of splicing categories?

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Explain the modifications of tRNA.

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Choose the correct answer from the list below. Not all of the answers will be used. -Nearly all mRNA precursors in higher eukaryotes are ______________.

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Diversity in proteins is due to _________________ of the same gene.

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Recognition of the 5` splice site by _________________ is the first step in splicing.

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What is the function of the 5` cap on mRNA transcripts?

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Diseases caused by mutations in pre-mRNA or in the splicing factors include:

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What is the catalytic chemistry of mRNA splicing?

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Choose the correct answer from the list below. Not all of the answers will be used. -______________ is/are elongated sequence(s) that stabilize(s) RNA.

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Guanosine cofactor is used in what mechanism?

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Choose the correct answer from the list below. Not all of the answers will be used. -A change, other than splicing, made to the base sequence of RNA following transcription is called ______________.

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