Question 1

Choose the correct answer from the list below. Not all of the answers will be used.
-____________ controls the synthesis and degradation of fructose 2,6-bisphosphate.

Accepted Answer

A) liver 
B) muscle 
C) one day 
D) endoplasmic reticulum 
E) gluconeogenesis
F)phosphoenolpyruvate carboxykinase
G)PFK2
H)Cori
I)fructose 2,6-bisphosphate
J)magnesium
K)oxaloacetate
L)biotin
M)2 hours
N)ATP 
A) liver 
B) muscle 
C) one day 
D) endoplasmic reticulum 
E) gluconeogenesis
F)phosphoenolpyruvate carboxykinase
G)PFK2
H)Cori
I)fructose 2,6-bisphosphate
J)magnesium
K)oxaloacetate
L)biotin
M)2 hours
N)ATP G

Question 2

How are gluconeogenesis and glycolysis coordinated by nucleotides?

Accepted Answer

ATP inhibits glycolysis at PFK, while ADP inhibits the flow of carbon from pyruvate to glucose at pyruvate carboxylase and phosphoenolpyruvate carboxykinase. When ADP levels are high, adenylate kinase converts ADP to AMP and ATP. The increase in AMP (only in a low-energy state) results in the inhibition of gluconeogenesis and activates glycolysis in the liver.

Question 3

Some amino acids are converted to glucose via conversion to pyruvate and ________________.

Accepted Answer

oxaloacetate

Question 4

Transport of oxaloacetate produced by PEPCK utilizes the mitochondrial and cytosolic enzyme ________________.

Accepted Answer

malate deh

Question 5

The primary raw materials for gluconeogenesis are:

Accepted Answer

A)  galactose and sucrose. 
B)  pyruvate and oxaloacetate. 
C)  lactate and amino acids. 
D)  fructose and glycerol. 
E)  lactose and lactate. 
A)  galactose and sucrose. 
B)  pyruvate and oxaloacetate. 
C)  lactate and amino acids. 
D)  fructose and glycerol. 
E)  lactose and lactate.

Question 6

Which of the following statements about PFK is correct?

Accepted Answer

A)  AMP and ADP both bind to and stabilize the inactive conformation of F6-P. 
B)  ATP can overcome the inhibition by citrate. 
C)  Citrate is an inhibitor of PFK. 
D)  Acidic conditions from anaerobic metabolism activate PFK. 
E)  None of the above. 
A)  AMP and ADP both bind to and stabilize the inactive conformation of F6-P. 
B)  ATP can overcome the inhibition by citrate. 
C)  Citrate is an inhibitor of PFK. 
D)  Acidic conditions from anaerobic metabolism activate PFK. 
E)  None of the above.

Question 7

The amount of glucose in the bloodstream and other body fluids is ________________.

Accepted Answer

The answer of The amount of glucose in the bloodstream...

Question 8

Adenosine monophosphate will have a(n) ________________ on PFK and a(n) ________________ effect on fructose 1,6-bisphosphatase.

Accepted Answer

activating

Question 9

Choose the correct answer from the list below. Not all of the answers will be used.
-The ____________ cycle is responsible for converting muscle lactate into glucose in the liver.

Accepted Answer

A) liver 
B) muscle 
C) one day 
D) endoplasmic reticulum 
E) gluconeogenesis
F)phosphoenolpyruvate carboxykinase
G)PFK2
H)Cori
I)fructose 2,6-bisphosphate
J)magnesium
K)oxaloacetate
L)biotin
M)2 hours
N)ATP 
A) liver 
B) muscle 
C) one day 
D) endoplasmic reticulum 
E) gluconeogenesis
F)phosphoenolpyruvate carboxykinase
G)PFK2
H)Cori
I)fructose 2,6-bisphosphate
J)magnesium
K)oxaloacetate
L)biotin
M)2 hours
N)ATP

Question 10

Eating raw eggs will lead to the ingestion of avidin, a compound that tightly binds to the head group of biotin.  What would be the result of this on a person's blood-sugar level?

Accepted Answer

The increase in avidin and dec

Question 11

Glucose 6-phosphatase takes place in which cellular location?

Accepted Answer

A)  the cytoplasm 
B)  the endoplasmic reticulum 
C)  the mitochondria 
D)  the nucleus 
E)  the plasma membrane 
A)  the cytoplasm 
B)  the endoplasmic reticulum 
C)  the mitochondria 
D)  the nucleus 
E)  the plasma membrane

Question 12

The gluconeogenesis step responsible for reversing pyruvate kinase is ________________.

Accepted Answer

The answer of The gluconeogenesis step responsible for reversing pyruvate...

Question 13

Biotin provides ________________ for the pyruvate carboxylase reaction.

Accepted Answer

A)  a long flexible arm for the active-site location of substrate 
B)  carboxylation of pyruvate 
C)  group transfer from one site of the enzyme to another 
D)  All of the above. 
E)  None of the above. 
A)  a long flexible arm for the active-site location of substrate 
B)  carboxylation of pyruvate 
C)  group transfer from one site of the enzyme to another 
D)  All of the above. 
E)  None of the above.

Question 14

The daily glucose requirement for a typical adult brain is ________________.

Accepted Answer

The answer of The daily glucose requirement for a typical...

Question 15

How are gluconeogenesis and glycolysis regulated reciprocally?

Accepted Answer

The enzymes involved in two substrate cy

Question 16

Choose the correct answer from the list below. Not all of the answers will be used.
-The process by which noncarbohydrate precursor molecules are converted into glucose is ____________.

Accepted Answer

A) liver 
B) muscle 
C) one day 
D) endoplasmic reticulum 
E) gluconeogenesis
F)phosphoenolpyruvate carboxykinase
G)PFK2
H)Cori
I)fructose 2,6-bisphosphate
J)magnesium
K)oxaloacetate
L)biotin
M)2 hours
N)ATP 
A) liver 
B) muscle 
C) one day 
D) endoplasmic reticulum 
E) gluconeogenesis
F)phosphoenolpyruvate carboxykinase
G)PFK2
H)Cori
I)fructose 2,6-bisphosphate
J)magnesium
K)oxaloacetate
L)biotin
M)2 hours
N)ATP

Question 17

Choose the correct answer from the list below. Not all of the answers will be used.
-____________: An intermediate that is decarboxylated and phosphorylated to produce phosphoenolpyruvate.

Accepted Answer

A) liver 
B) muscle 
C) one day 
D) endoplasmic reticulum 
E) gluconeogenesis
F)phosphoenolpyruvate carboxykinase
G)PFK2
H)Cori
I)fructose 2,6-bisphosphate
J)magnesium
K)oxaloacetate
L)biotin
M)2 hours
N)ATP 
A) liver 
B) muscle 
C) one day 
D) endoplasmic reticulum 
E) gluconeogenesis
F)phosphoenolpyruvate carboxykinase
G)PFK2
H)Cori
I)fructose 2,6-bisphosphate
J)magnesium
K)oxaloacetate
L)biotin
M)2 hours
N)ATP

Question 18

High levels of ATP and citrate:

Accepted Answer

A)  indicate a high-energy-well-fed state. 
B)  promote gluconeogenesis. 
C)  inhibit glycolysis. 
D)  All of the above. 
E)  None of the above. 
A)  indicate a high-energy-well-fed state. 
B)  promote gluconeogenesis. 
C)  inhibit glycolysis. 
D)  All of the above. 
E)  None of the above.

Question 19

Insulin resistance is a hallmark of:

Accepted Answer

A)  PEPCK activation 
B)  pancreatic disorder 
C)  Type 1 diabetes 
D)  Type 2 diabetes 
E)  long-term starvation 
A)  PEPCK activation 
B)  pancreatic disorder 
C)  Type 1 diabetes 
D)  Type 2 diabetes 
E)  long-term starvation

Question 20

Allosteric activators of gluconeogenesis are going to  __________the flux of carbon to glucose.

Accepted Answer

The answer of Allosteric activators of gluconeogenesis are going to...

Exam 17: Gluconeogenesis

Choose the correct answer from the list below. Not all of the answers will be used. -____________ controls the synthesis and degradation of fructose 2,6-bisphosphate.

How are gluconeogenesis and glycolysis coordinated by nucleotides?

Some amino acids are converted to glucose via conversion to pyruvate and ________________.

Transport of oxaloacetate produced by PEPCK utilizes the mitochondrial and cytosolic enzyme ________________.

The primary raw materials for gluconeogenesis are:

Which of the following statements about PFK is correct?

The amount of glucose in the bloodstream and other body fluids is ________________.

Adenosine monophosphate will have a(n) ________________ on PFK and a(n) ________________ effect on fructose 1,6-bisphosphatase.

Choose the correct answer from the list below. Not all of the answers will be used. -The ____________ cycle is responsible for converting muscle lactate into glucose in the liver.

Eating raw eggs will lead to the ingestion of avidin, a compound that tightly binds to the head group of biotin. What would be the result of this on a person's blood-sugar level?

Glucose 6-phosphatase takes place in which cellular location?

The gluconeogenesis step responsible for reversing pyruvate kinase is ________________.

Biotin provides ________________ for the pyruvate carboxylase reaction.

The daily glucose requirement for a typical adult brain is ________________.

How are gluconeogenesis and glycolysis regulated reciprocally?

Choose the correct answer from the list below. Not all of the answers will be used. -The process by which noncarbohydrate precursor molecules are converted into glucose is ____________.

Choose the correct answer from the list below. Not all of the answers will be used. -____________: An intermediate that is decarboxylated and phosphorylated to produce phosphoenolpyruvate.

High levels of ATP and citrate:

Insulin resistance is a hallmark of:

Allosteric activators of gluconeogenesis are going to __________the flux of carbon to glucose.

Biochemistry and the Unity of Life

Water, Weak Bonds, and the Generation of Order Out of Chaos

Amino Acids

Protein Three-Dimensional Structure

Techniques in Protein Biochemistry

Basic Concepts of Enzyme Action

Kinetics and Regulation

Mechanisms and Inhibitors

Hemoglobin: an Allosteric Protein

Carbohydrates

Lipids

Membrane Structure and Function

Signal Transduction Pathways

Digestion: Turning a Meal Into Cellular Biochemicals

Metabolism: Basic Concepts and Design

Glycolysis

Preparation for the Cycle

Harvesting Electrons From the Cycle

The Electron Transport Chain

The Proton-Motive Force

The Light Reactions

The Calvin Cycle

Glycogen Degradation

Glycogen Synthesis

The Pentose Phosphate Pathway

Fatty Acid Degredation

Fatty Acid Synthesis

Lipid Synthesis

Amino Acid Degradation and the Urea Cycle

Amino Acids Synthesis

Nucleotide Metabolism

The Structure of Informational Macromolecules: Dna and Rna

DNA Replication

DNA Repair and Recombination

RNA Synthesis and Regulation in Prokaryotes

Gene Expression in Eukaryotes

RNA Processing in Eukaryotes

The Genetic Code

The Mechanism of Protein Synthesis

Recombinant DNA Techniques

Filters

Adenosine monophosphate will have a(n) on PFK and a(n) effect on fructose 1,6-bisphosphatase.