Question 1

Nuclear hormone receptors bind to specific DNA sites known as ________________.

Accepted Answer

response elements

Question 2

Choose the correct answer from the list below. Not all of the answers will be used.
-______________ is a region of a protein that regulates transcription by interacting with the acetylated lysine of histones.

Accepted Answer

A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger 
A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger B

Question 3

Why must gene regulation be more complicated in eukaryotic cells when compared to prokaryotic cells?

Accepted Answer

Eukaryotic cells do not contain operons for coordinate regulation. Furthermore, there are many different cell types, which all require differential regulation of the genes made. Finally, there are many more genes spread across eukaryotic genomes.

Question 4

A key reaction in gene repression is the deacetylation of this/these amino acids in histones:

Accepted Answer

A)  serine. 
B)  threonine. 
C)  arginine. 
D)  lysine. 
E)  All of the above. 
A)  serine. 
B)  threonine. 
C)  arginine. 
D)  lysine. 
E)  All of the above.

Question 5

Explain why different RNA polymerases transcribe specific genes and only those genes.

Accepted Answer

The promoter sites for each RNA polymera

Question 6

Enhancer sites are often located:

Accepted Answer

A)  near the poly(
A)  tail site. 
B)  within introns. 
C)  at a distance from the transcription start site. 
D)  All of the above. 
E)  None of the above. 
A)  near the poly(
A)  tail site. 
B)  within introns. 
C)  at a distance from the transcription start site. 
D)  All of the above. 
E)  None of the above.

Question 7

How does a coactivator function in gene expression?

Accepted Answer

The binding of ligand to the receptor in

Question 8

What additional complexities exist between gene expression in eukaryotes but not in prokaryotes?

Accepted Answer

Regulation of transcription of a gene in

Question 9

A common selective estrogen receptor modulator used in breast cancer therapy is:

Accepted Answer

A)  tamoxifen. 
B)  α-amanitin 
C)  acetyl-lysine binding protein (ALBP) 
D)  All of the above 
E)  None of the above. 
A)  tamoxifen. 
B)  α-amanitin 
C)  acetyl-lysine binding protein (ALBP) 
D)  All of the above 
E)  None of the above.

Question 10

When phosphorylated, the carboxyl-terminal domain of RNA polymerase II:

Accepted Answer

A)  is insensitive to α-amanitin. 
B)  enhances transcription. 
C)  recruits other factors. 
D)  A and C. 
E)  B and C. 
A)  is insensitive to α-amanitin. 
B)  enhances transcription. 
C)  recruits other factors. 
D)  A and C. 
E)  B and C.

Question 11

In eukaryotes, DNA-binding proteins bind to DNA by which of the following DNA-binding structures?

Accepted Answer

A)  the zinc-finger domain 
B)  the cAMP binding 
C)  closed loops called lariats 
D)  A and B 
E)  A, B, and C 
A)  the zinc-finger domain 
B)  the cAMP binding 
C)  closed loops called lariats 
D)  A and B 
E)  A, B, and C

Question 12

Briefly describe the path of a steroid hormone in gene regulation.

Accepted Answer

The steroid hormones can diffuse across

Question 13

Why must gene regulation be more complicated in eukaryotic cells when compared to prokaryotic cells?

Accepted Answer

Eukaryotic cells do not contain operons

Question 14

What additional complexities exist between gene expression in eukaryotes but not in prokaryotes?

Accepted Answer

Regulation of transcription of a gene in

Question 15

Choose the correct answer from the list below. Not all of the answers will be used.
-Binding sites in DNA for specific regulatory proteins are called ______________.

Accepted Answer

A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger 
A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger

Question 16

Choose the correct answer from the list below. Not all of the answers will be used.
-______________ is a general term for molecules that bind to receptors.

Accepted Answer

A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger 
A) enhancers 
B) bromodomain 
C) regulated 
D) chromatin-remodeling engines 
E) ligand
F)coactivators
G)agonists
H)histone acetylase
I)citrate
J)TATA box
K)histone deacetylase
L)zinc finger

Question 17

What is the role of a mediator in transcription?

Accepted Answer

A mediator is a bridge, compos

Question 18

Molecules that bind to a receptor and trigger signaling pathways are called:

Accepted Answer

A)  antagonists. 
B)  agonists. 
C)  IRE-binding proteins. 
D)  promoters. 
E)  None of the above. 
A)  antagonists. 
B)  agonists. 
C)  IRE-binding proteins. 
D)  promoters. 
E)  None of the above.

Question 19

How does a coactivator function in gene expression?

Accepted Answer

The binding of a ligand to the receptor

Question 20

_____ receptors differ from cell surface receptors in that they are soluble cytoplasmic proteins.

Accepted Answer

The answer of _____ receptors differ from cell surface receptors...

Exam 37: Gene Expression in Eukaryotes

Nuclear hormone receptors bind to specific DNA sites known as ________________.

Choose the correct answer from the list below. Not all of the answers will be used. -______________ is a region of a protein that regulates transcription by interacting with the acetylated lysine of histones.

Why must gene regulation be more complicated in eukaryotic cells when compared to prokaryotic cells?

A key reaction in gene repression is the deacetylation of this/these amino acids in histones:

Explain why different RNA polymerases transcribe specific genes and only those genes.

Enhancer sites are often located:

How does a coactivator function in gene expression?

What additional complexities exist between gene expression in eukaryotes but not in prokaryotes?

A common selective estrogen receptor modulator used in breast cancer therapy is:

When phosphorylated, the carboxyl-terminal domain of RNA polymerase II:

In eukaryotes, DNA-binding proteins bind to DNA by which of the following DNA-binding structures?

Briefly describe the path of a steroid hormone in gene regulation.

Why must gene regulation be more complicated in eukaryotic cells when compared to prokaryotic cells?

What additional complexities exist between gene expression in eukaryotes but not in prokaryotes?

Choose the correct answer from the list below. Not all of the answers will be used. -Binding sites in DNA for specific regulatory proteins are called ______________.

Choose the correct answer from the list below. Not all of the answers will be used. -______________ is a general term for molecules that bind to receptors.

What is the role of a mediator in transcription?

Molecules that bind to a receptor and trigger signaling pathways are called:

How does a coactivator function in gene expression?

_____ receptors differ from cell surface receptors in that they are soluble cytoplasmic proteins.

Biochemistry and the Unity of Life

Water, Weak Bonds, and the Generation of Order Out of Chaos

Amino Acids

Protein Three-Dimensional Structure

Techniques in Protein Biochemistry

Basic Concepts of Enzyme Action

Kinetics and Regulation

Mechanisms and Inhibitors

Hemoglobin: an Allosteric Protein

Carbohydrates

Lipids

Membrane Structure and Function

Signal Transduction Pathways

Digestion: Turning a Meal Into Cellular Biochemicals

Metabolism: Basic Concepts and Design

Glycolysis

Gluconeogenesis

Preparation for the Cycle

Harvesting Electrons From the Cycle

The Electron Transport Chain

The Proton-Motive Force

The Light Reactions

The Calvin Cycle

Glycogen Degradation

Glycogen Synthesis

The Pentose Phosphate Pathway

Fatty Acid Degredation

Fatty Acid Synthesis

Lipid Synthesis

Amino Acid Degradation and the Urea Cycle

Amino Acids Synthesis

Nucleotide Metabolism

The Structure of Informational Macromolecules: Dna and Rna

DNA Replication

DNA Repair and Recombination

RNA Synthesis and Regulation in Prokaryotes

RNA Processing in Eukaryotes

The Genetic Code

The Mechanism of Protein Synthesis

Recombinant DNA Techniques

Filters