Exam 19: Cellular Mechanisms of Development

If cells from a wing are transplanted to the leg prior to their determination, into what will they likely develop?

The low success rate and age-related diseases associated with reproductive cloning is thought to be due to

A zygote is a fertilized egg formed by an egg and a sperm.The zygote undergoes many mitotic events as it develops into a solid ball of cells (ie, blastomeres) called a blastula.What changes occur in this early cleavage?

In Drosophila, the cells created by cleavage contain different developmental signals from the egg called cytoplasmic

Very early in development, each cell is capable of expressing all its genes.This is referred to as

You created a worm that expresses a human Bcl-2 transgene, and you are crossing the transgene into a homozygous ced-9 mutant background.However, you inadvertantly used a clone of Bcl-2 with a mutation in the BH domain, which is essential for function.What results do you expect for the ced-9 mutants with the mutant Bcl-2 transgene?

Cells that are programmed to die, shrivel and shrink in a process called

In insects, the passage from one body form to another is called

Briggs and King demonstrated nuclear transplantation in

In contrast to the cell cycle of adult somatic cells, the dividing cells of an early embryo lack which cell cycle stage(s)?

In general, the blastomeres of this region form the ectodermal tissues.

In C. elegans ced-9/ced-3 double mutants

These are cell adhesion proteins that some cells use in the process of differentiation during development.

What can be said about Drosophila development?

In a 32-cell stage tunicate embryo, vegetal marginal cells that lack functional genes for both macho-1 and the FGF receptor would develop as what cell type?

You have discovered a new gene similar to an integrin.If you misexpress this gene in the wrong tissue early in development, what is a likely phenotype?

Adult stem cells are usually

Many insects, like moths and flies, undergo complete metamorphosis.What would you predict about gene expression in these two kinds of insects?

What is the correct order of gene expression in the early Drosophila embryo?

Overexpression of caudal in the early Drosophila embryo, at a level high enough to overcome inhibition by Bicoid protein, would