Question 1

How many Barr bodies does a normal human female contain in each diploid cell?

Accepted Answer

A) 0 
B) 1 
C) 2 
D) 3 
A) 0 
B) 1 
C) 2 
D) 3 B

Question 2

The number of allele pairs that assort independently in an organism is generally much higher than the number of chromosome pairs.This phenomenon is due to

Accepted Answer

A) independent assortment. 
B) segregation. 
C) crossing over. 
D) sex-linkage. 
A) independent assortment. 
B) segregation. 
C) crossing over. 
D) sex-linkage. C

Question 3

Occasionally, chromosomes fail to separate during meiosis, leading to daughter cells that have an abnormal number of chromosomes.This phenomenon is called

Accepted Answer

A) epistasis. 
B) nondisjunction. 
C) crossing over. 
D) pleiotropy. 
A) epistasis. 
B) nondisjunction. 
C) crossing over. 
D) pleiotropy. B

Question 4

_______________ is a human hereditary disease that is caused by a dominant allele but does not show up in affected individuals until they are in middle age.

Accepted Answer

A) Cystic fibrosis 
B) Sickle cell anemia 
C) Tay-Sachs disease 
D) Huntington's disease 
A) Cystic fibrosis 
B) Sickle cell anemia 
C) Tay-Sachs disease 
D) Huntington's disease

Question 5

In sickle cell anemia, the defective hemoglobin differs from the normal hemoglobin by

Accepted Answer

A) the color of the pigment. 
B) the size of the molecule. 
C) a single amino acid substitution. 
D) the total number of amino acids. 
A) the color of the pigment. 
B) the size of the molecule. 
C) a single amino acid substitution. 
D) the total number of amino acids.

Question 6

Sickle cell anemia is caused by a defect in the

Accepted Answer

A) oxygen-carrying pigment hemoglobin. 
B) ability of the blood to clot. 
C) ability of red blood cells to fight infection. 
D) chloride ion transport protein. 
A) oxygen-carrying pigment hemoglobin. 
B) ability of the blood to clot. 
C) ability of red blood cells to fight infection. 
D) chloride ion transport protein.

Question 7

If you needed to determine the order of genes on a chromosome, you should perform

Accepted Answer

A) a test cross. 
B) a two-point cross. 
C) a three-point cross. 
D) a SNP test. 
A) a test cross. 
B) a two-point cross. 
C) a three-point cross. 
D) a SNP test.

Question 8

Genetic exchange between 2 homologous chromosomes is called

Accepted Answer

A) synapsis. 
B) pleiotropy. 
C) crossing over. 
D) allelic exchange. 
A) synapsis. 
B) pleiotropy. 
C) crossing over. 
D) allelic exchange.

Question 9

A human female with only one X chromosome is said to have a condition called

Accepted Answer

A) X chromosome inactivation. 
B) Angelman syndrome. 
C) Turner syndrome. 
D) Klinefelter syndrome. 
A) X chromosome inactivation. 
B) Angelman syndrome. 
C) Turner syndrome. 
D) Klinefelter syndrome.

Question 10

Why can't you use mitochondrial DNA to distinguish between these two suspects?

Accepted Answer

A) The sequence of mitochondrial DNA has not yet been determined. 
B) The brothers share the same mitochondrial DNA. 
C) There are no molecular techniques available that allow one to analyze mitochondrial DNA. 
D) Because mitochondrial DNA is inherited in a paternal pattern. 
A) The sequence of mitochondrial DNA has not yet been determined. 
B) The brothers share the same mitochondrial DNA. 
C) There are no molecular techniques available that allow one to analyze mitochondrial DNA. 
D) Because mitochondrial DNA is inherited in a paternal pattern.

Question 11

In humans, if non-disjunction led to an individual with a genotype of XO, that person would

Accepted Answer

A) be female because each cell lacks a Y chromosome. 
B) be male because each cell has only one X chromosome. 
C) display both male and female characteristics. 
D) not survive. 
A) be female because each cell lacks a Y chromosome. 
B) be male because each cell has only one X chromosome. 
C) display both male and female characteristics. 
D) not survive.

Question 12

Humans who have lost one copy of an autosome are called

Accepted Answer

A) haploid. 
B) trisomic. 
C) bisomic. 
D) monosomic. 
A) haploid. 
B) trisomic. 
C) bisomic. 
D) monosomic.

Question 13

Which statement about calico cats is false?

Accepted Answer

A) Calico cats can be male or female. 
B) The different colored fur is due to the inactivation of one X chromosome. 
C) The variation in coat color is an example of an epistatic interaction. 
D) Calico cats are genetic mosaics. 
A) Calico cats can be male or female. 
B) The different colored fur is due to the inactivation of one X chromosome. 
C) The variation in coat color is an example of an epistatic interaction. 
D) Calico cats are genetic mosaics.

Question 14

In Morgan's experiments, the white eye allele in Drosophila was shown to be

Accepted Answer

A) located on the X chromosome. 
B) located on the Y chromosome. 
C) dominant. 
D) located on an autosome. 
A) located on the X chromosome. 
B) located on the Y chromosome. 
C) dominant. 
D) located on an autosome.

Question 15

Hemophilia is caused by a

Accepted Answer

A) recessive allele on the X chromosome. 
B) dominant allele on the X chromosome. 
C) codominant allele on the X chromosome. 
D) recessive allele on an autosome. 
A) recessive allele on the X chromosome. 
B) dominant allele on the X chromosome. 
C) codominant allele on the X chromosome. 
D) recessive allele on an autosome.

Question 16

Nondisjunction of a single pair of autosomes can lead to all of the following except

Accepted Answer

A) aneuploidy. 
B) monosomy. 
C) trisomy. 
D) euploidy. 
A) aneuploidy. 
B) monosomy. 
C) trisomy. 
D) euploidy.

Question 17

In humans, if an XY individual had a deletion of the SYR gene, that person would

Accepted Answer

A) develop as a female. 
B) have both male and female characteristics. 
C) have ambiguous genitalia. 
D) develop as a male. 
A) develop as a female. 
B) have both male and female characteristics. 
C) have ambiguous genitalia. 
D) develop as a male.

Question 18

What is the relationship between recombination frequency and the actual physical distance on a chromosome?

Accepted Answer

A) As physical distance increases, the recombination frequency increases in a linear fashion. 
B) As physical distance increases, the recombination frequency decreases in a linear fashion. 
C) As physical distance increases, the recombination frequency first increases in a linear fashion, but gradually levels off to a frequency of 0.5. 
D) As physical distance increases, the recombination frequency first increases, but then decreases. 
A) As physical distance increases, the recombination frequency increases in a linear fashion. 
B) As physical distance increases, the recombination frequency decreases in a linear fashion. 
C) As physical distance increases, the recombination frequency first increases in a linear fashion, but gradually levels off to a frequency of 0.5. 
D) As physical distance increases, the recombination frequency first increases, but then decreases.

Question 19

Given that these two gene loci are very closely linked, the phenotypic ratio in the F2 generation should be closest to

Accepted Answer

A) 1 brown eye, heavy wing veins: 2 red eye, thin wing veins: 1 brown eye, thin wing veins 
B) 1 brown eye, thin wing veins: 2 red eye, thin wing veins: 1 red eye, heavy wing veins 
C) 3 red eye, thin wing veins: 1 brown eye, heavy wing veins 
D) 1 brown eye: 1 red eye: 1 heavy wing veins: 1 thin wing veins 
A) 1 brown eye, heavy wing veins: 2 red eye, thin wing veins: 1 brown eye, thin wing veins 
B) 1 brown eye, thin wing veins: 2 red eye, thin wing veins: 1 red eye, heavy wing veins 
C) 3 red eye, thin wing veins: 1 brown eye, heavy wing veins 
D) 1 brown eye: 1 red eye: 1 heavy wing veins: 1 thin wing veins

Question 20

A genetic _____ indicates the distances between gene loci measured in terms of the frequency of recombination.

Accepted Answer

A) map 
B) profile 
C) pedigree 
D) clone 
A) map 
B) profile 
C) pedigree 
D) clone

Exam 13: Chromosomes, Mapping, and the Meiosis-Inheritance Connection

How many Barr bodies does a normal human female contain in each diploid cell?

The number of allele pairs that assort independently in an organism is generally much higher than the number of chromosome pairs.This phenomenon is due to

Occasionally, chromosomes fail to separate during meiosis, leading to daughter cells that have an abnormal number of chromosomes.This phenomenon is called

_______________ is a human hereditary disease that is caused by a dominant allele but does not show up in affected individuals until they are in middle age.

In sickle cell anemia, the defective hemoglobin differs from the normal hemoglobin by

Sickle cell anemia is caused by a defect in the

If you needed to determine the order of genes on a chromosome, you should perform

Genetic exchange between 2 homologous chromosomes is called

A human female with only one X chromosome is said to have a condition called

Why can't you use mitochondrial DNA to distinguish between these two suspects?

In humans, if non-disjunction led to an individual with a genotype of XO, that person would

Humans who have lost one copy of an autosome are called

Which statement about calico cats is false?

In Morgan's experiments, the white eye allele in Drosophila was shown to be

Hemophilia is caused by a

Nondisjunction of a single pair of autosomes can lead to all of the following except

In humans, if an XY individual had a deletion of the SYR gene, that person would

What is the relationship between recombination frequency and the actual physical distance on a chromosome?

Given that these two gene loci are very closely linked, the phenotypic ratio in the F2 generation should be closest to

A genetic _____ indicates the distances between gene loci measured in terms of the frequency of recombination.

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Given that these two gene loci are very closely linked, the phenotypic ratio in the F₂ generation should be closest to