Exam 11: DNA Structure, Replication, and Repair

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Match each researcher or set of researchers with the discovery or experiment each is associated with. -worked out the double helix model for DNA structure

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Suppose that you performed a version of the Hershey and Chase experiment, this time using 32P-labelled viruses that insert their DNA into the DNA of the cells that they infect. Also suppose that the viral DNA is then treated as part of the cell's own DNA, and is replicated during DNA replication and passed on to daughter cells when the cell divides. You infect a population of cells with the 32P-labelled viruses, and then let the infected cells go through two generations of cell divisions. In how many cells should you find 32P-labelled DNA?

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What would be the error rate in DNA replication if the proofreading ability of DNA polymerase were to be removed?

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What is meant by the term antiparallel, when applied to DNA structure?

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Which nitrogenous bases are considered pyrimidines?

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What were the T2 bacteriophages used in the Hershey and Chase experiment made of?

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Which sentence describes the width of a DNA double helix?

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What adds individual nucleotides to the 3' end of an existing strand to build a new DNA strand during DNA replication?

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During normal DNA replication, why is part of the DNA at the ends of linear chromosomes NOT copied into the new DNA strands?

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Suppose that the DNA of an organism is studied and found to contain 14% guanine. What percentage of thymine would you expect to find?

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What is the function of telomerase in humans?

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What catalyzes the unwinding of the DNA double helix during DNA replication?

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Which nitrogenous bases are considered purines?

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Match each researcher or set of researchers with the discovery or experiment each is associated with. -showed that DNA is the transforming principle, from heat-killed S strain Streptococcus pneumoniae that can make the R strain virulent

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From his work with Streptococcus pneumoniae bacteria, Griffith described the transforming principle. What did this principle prove to be?

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Suppose that the DNA of an organism is studied and found to contain 30% adenine. Based on this information, what percentage of thymine would you predict that the DNA of this organism would also contain?

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Which of the following acts to remove twisting and strain ahead of the replication fork during DNA replication?

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