Question 1

From which of the following stem cells are eosinophils derived?

Accepted Answer

A) CLP 
B) CMP 
C) CEP 
D) Both CLP and CMP. 
E) None of the answers are correct. 
A) CLP 
B) CMP 
C) CEP 
D) Both CLP and CMP. 
E) None of the answers are correct. B

Question 2

Naïve lymphocytes enter secondary lymphoid tissues via which of the following structures?

Accepted Answer

A) Afferent lymphatics 
B) Efferent lymphatics 
C) HEVs 
D) Marginal sinus 
E) None of the answers are correct. 
A) Afferent lymphatics 
B) Efferent lymphatics 
C) HEVs 
D) Marginal sinus 
E) None of the answers are correct. C

Question 3

Which of the following cell types is responsible for regulating responses against intracellular pathogens?

Accepted Answer

A) TH1 
B) TH2 
C) TH17 
D) TFH 
E) Plasma cell 
A) TH1 
B) TH2 
C) TH17 
D) TFH 
E) Plasma cell A

Question 4

Which of the following is NOT true about monocytes?

Accepted Answer

A) They comprise between 5%-10% of circulating leukocytes. 
B) They have the ability to differentiate into macrophages or dendritic cells. 
C) They can be subdivided into inflammatory monocytes and patrolling monocytes. 
D) They can give rise to platelets. 
E) All of the answers are true. 
A) They comprise between 5%-10% of circulating leukocytes. 
B) They have the ability to differentiate into macrophages or dendritic cells. 
C) They can be subdivided into inflammatory monocytes and patrolling monocytes. 
D) They can give rise to platelets. 
E) All of the answers are true.

Question 5

From which of the following stem cells are RBCs derived?

Accepted Answer

A) CLP 
B) CMP 
C) CEP 
D) Both CLP and CMP. 
E) None of the answers are correct. 
A) CLP 
B) CMP 
C) CEP 
D) Both CLP and CMP. 
E) None of the answers are correct.

Question 6

What important role do antibodies play in the isolation of HSCs from the bone marrow?

Accepted Answer

Antibodies can be used to eliminate bone

Question 7

From which of the following stem cells are monocytes derived?

Accepted Answer

A) CLP 
B) CMP 
C) CEP 
D) Both CLP and CMP. 
E) None of the answers are correct. 
A) CLP 
B) CMP 
C) CEP 
D) Both CLP and CMP. 
E) None of the answers are correct.

Question 8

You have consumed a salad contaminated with Salmonella enterica, which typically causes a self-limiting, gastrointestinal disease in humans.Based on this information, which immune organ is MOST likely to first recognize and mount a response against the pathogen?

Accepted Answer

A) Spleen 
B) SALT 
C) Thymus 
D) GALT 
E) Lymph node 
A) Spleen 
B) SALT 
C) Thymus 
D) GALT 
E) Lymph node

Question 9

Which of the following effector T lymphocyte populations is produced via the activation of a naïve T cell through antigen presented in MHC Class I?

Accepted Answer

A) CTL 
B) TH1 
C) TH2 
D) TH17 
E) None of the answers are correct. 
A) CTL 
B) TH1 
C) TH2 
D) TH17 
E) None of the answers are correct.

Question 10

From which of the following stem cells are NK cells derived?

Accepted Answer

A) CLP 
B) CMP 
C) CEP 
D) Both CLP and CMP are correct. 
E) None of the answers are correct. 
A) CLP 
B) CMP 
C) CEP 
D) Both CLP and CMP are correct. 
E) None of the answers are correct.

Question 11

Which of the following granulocytes contains histamine within its granules?

Accepted Answer

A) Neutrophils 
B) Eosinophils 
C) Basophils 
D) Both Eosinophils and Basophils 
E) All of the answers are correct. 
A) Neutrophils 
B) Eosinophils 
C) Basophils 
D) Both Eosinophils and Basophils 
E) All of the answers are correct.

Question 12

Which of the following does NOT appear to utilize the FRCC system as its primary means for trafficking through the lymph node?

Accepted Answer

A) B cells 
B) T cells 
C) Free antigen that entered via an afferent lymphatic 
D) Cytokines and chemokines 
E) None of the answers utilizes the FRCC system. 
A) B cells 
B) T cells 
C) Free antigen that entered via an afferent lymphatic 
D) Cytokines and chemokines 
E) None of the answers utilizes the FRCC system.

Question 13

Which of the following cell types is responsible for activating B cells in germinal centers?

Accepted Answer

A) TH1 
B) TH2 
C) TH17 
D) TFH 
E) Plasma cell 
A) TH1 
B) TH2 
C) TH17 
D) TFH 
E) Plasma cell

Question 14

What level of gene expression is regulated by such factors as Notch1, GATA-2 and Bmi-1?

Accepted Answer

A) Replication 
B) Transcription 
C) RNA processing 
D) Translation 
E) None of the answers are correct. 
A) Replication 
B) Transcription 
C) RNA processing 
D) Translation 
E) None of the answers are correct.

Question 15

Plasma cells can secrete thousands of antibodies per second.Based on this observation, name two organelles that you might expect to find in abundance within an active plasma cell.

Accepted Answer

An abundance of Golgi and endo

Question 16

Which cell can differentiate into the GREATEST variety of cells during hematopoiesis?

Accepted Answer

A) B-cell progenitor 
B) Basophil progenitor 
C) T-cell progenitor 
D) Eosinophil progenitor 
E) Myeloid progenitor 
A) B-cell progenitor 
B) Basophil progenitor 
C) T-cell progenitor 
D) Eosinophil progenitor 
E) Myeloid progenitor

Question 17

As thymocytes develop, they are classified on the basis of the state of their T-cell receptors and which of the following?

Accepted Answer

A) Which class of MHC they express on their surface 
B) The state of the immunoglobulin heavy and light chains on their surface 
C) The presence of coreceptor proteins CD4 and CD8 on their surface 
D) The expression of the transcription factor, FoxP3 
E) None of the answers are correct. 
A) Which class of MHC they express on their surface 
B) The state of the immunoglobulin heavy and light chains on their surface 
C) The presence of coreceptor proteins CD4 and CD8 on their surface 
D) The expression of the transcription factor, FoxP3 
E) None of the answers are correct.

Question 18

Beyond structural differences, name functional differences between a lymph node and the spleen.

Accepted Answer

Two major functional differences exist w

Question 19

Which of the following cell types is responsible for regulating responses against predominantly extracellular pathogens?

Accepted Answer

A) TH1 
B) TH2 
C) TH17 
D) TFH 
E) Plasma cell 
A) TH1 
B) TH2 
C) TH17 
D) TFH 
E) Plasma cell

Question 20

A pluripotent stem cell can do which of the following?

Accepted Answer

A) Differentiate into a finite number of different cell types 
B) Differentiate into any type of cell found in the adult 
C) Divide an infinite number of times 
D) All of the answers are correct. 
E) None of the answers are correct. 
A) Differentiate into a finite number of different cell types 
B) Differentiate into any type of cell found in the adult 
C) Divide an infinite number of times 
D) All of the answers are correct. 
E) None of the answers are correct.

From which of the following stem cells are eosinophils derived?

Naïve lymphocytes enter secondary lymphoid tissues via which of the following structures?

Which of the following cell types is responsible for regulating responses against intracellular pathogens?

Which of the following is NOT true about monocytes?

From which of the following stem cells are RBCs derived?

What important role do antibodies play in the isolation of HSCs from the bone marrow?

From which of the following stem cells are monocytes derived?

You have consumed a salad contaminated with Salmonella enterica, which typically causes a self-limiting, gastrointestinal disease in humans.Based on this information, which immune organ is MOST likely to first recognize and mount a response against the pathogen?

Which of the following effector T lymphocyte populations is produced via the activation of a naïve T cell through antigen presented in MHC Class I?

From which of the following stem cells are NK cells derived?

Which of the following granulocytes contains histamine within its granules?

Which of the following does NOT appear to utilize the FRCC system as its primary means for trafficking through the lymph node?

Which of the following cell types is responsible for activating B cells in germinal centers?

What level of gene expression is regulated by such factors as Notch1, GATA-2 and Bmi-1?

Plasma cells can secrete thousands of antibodies per second.Based on this observation, name two organelles that you might expect to find in abundance within an active plasma cell.

Which cell can differentiate into the GREATEST variety of cells during hematopoiesis?

As thymocytes develop, they are classified on the basis of the state of their T-cell receptors and which of the following?

Beyond structural differences, name functional differences between a lymph node and the spleen.

Which of the following cell types is responsible for regulating responses against predominantly extracellular pathogens?

A pluripotent stem cell can do which of the following?

Overview of the Immune System

Recognition and Response

Innate Immunity

The Complement System

The Organization and Expression of Lymphocyte Receptor Genes

The Major Histocompatibility Complex and Antigen Presentation

T-Cell Development

B-Cell Development

T-Cell Activation, Differentiation, and Memory

B-Cell Activation, Differentiation, and Memory

Effector Responses: Cell- and Antibody-Mediated Immunity

Mucosal Immunity and the Microbiome

The Immune Response in Time and Space

Allergy, Hypersensitivities, and Chronic Inflammation

Tolerance, Autoimmunity, and Transplantation

Infectious Diseases and Vaccines

Immunodeficiency Disorders

Cancer and the Immune System

Experimental Methods and Systems

Filters

Exam 2: Cells, Organs, and Microenvironments of the Immune System

From which of the following stem cells are eosinophils derived?

Naïve lymphocytes enter secondary lymphoid tissues via which of the following structures?

Which of the following cell types is responsible for regulating responses against intracellular pathogens?

Which of the following is NOT true about monocytes?

From which of the following stem cells are RBCs derived?

What important role do antibodies play in the isolation of HSCs from the bone marrow?

From which of the following stem cells are monocytes derived?

You have consumed a salad contaminated with Salmonella enterica, which typically causes a self-limiting, gastrointestinal disease in humans.Based on this information, which immune organ is MOST likely to first recognize and mount a response against the pathogen?

Which of the following effector T lymphocyte populations is produced via the activation of a naïve T cell through antigen presented in MHC Class I?

From which of the following stem cells are NK cells derived?

Which of the following granulocytes contains histamine within its granules?

Which of the following does NOT appear to utilize the FRCC system as its primary means for trafficking through the lymph node?

Which of the following cell types is responsible for activating B cells in germinal centers?

What level of gene expression is regulated by such factors as Notch1, GATA-2 and Bmi-1?

Plasma cells can secrete thousands of antibodies per second.Based on this observation, name two organelles that you might expect to find in abundance within an active plasma cell.

Which cell can differentiate into the GREATEST variety of cells during hematopoiesis?

As thymocytes develop, they are classified on the basis of the state of their T-cell receptors and which of the following?

Beyond structural differences, name functional differences between a lymph node and the spleen.

Which of the following cell types is responsible for regulating responses against predominantly extracellular pathogens?

A pluripotent stem cell can do which of the following?

Overview of the Immune System

Recognition and Response

Innate Immunity

The Complement System

The Organization and Expression of Lymphocyte Receptor Genes

The Major Histocompatibility Complex and Antigen Presentation

T-Cell Development

B-Cell Development

T-Cell Activation, Differentiation, and Memory

B-Cell Activation, Differentiation, and Memory

Effector Responses: Cell- and Antibody-Mediated Immunity

Mucosal Immunity and the Microbiome

The Immune Response in Time and Space

Allergy, Hypersensitivities, and Chronic Inflammation

Tolerance, Autoimmunity, and Transplantation

Infectious Diseases and Vaccines

Immunodeficiency Disorders

Cancer and the Immune System

Experimental Methods and Systems

Filters