Question 1

7TM is an abbreviation for ________________ receptors.

Accepted Answer

seven-tran

Question 2

Protein kinase A phosphorylates serine and ________________ residues.

Accepted Answer

The answer of Protein kinase A phosphorylates serine and ________________...

Question 3

Describe the role of phosphoinositol 4,5-bisphosphate (PIP2) in insulin signal transduction.

Accepted Answer

PIP2 is one of the signal molecules in t

Question 4

What steps lead from the activation of a cross-phosphorylated receptor tyrosine kinase to an activated small G protein such as Ras?

Accepted Answer

The phosphorylated receptor bi

Question 5

Choose the correct answer from the list below. Not all of the answers will be used.
-Ras is a member of the ____________ family of proteins.

Accepted Answer

A) protein kinase A (PK
A)  
B) calmodulin 
C) fatty acids 
D) proto-oncogene 
E) R2C2
F)R1C2
G)cAMP
H)phospholipase C
I)protein kinase C (PK
C) 
J)epinephrine
K)oncogene
L)small G proteins 
A) protein kinase A (PK
A)  
B) calmodulin 
C) fatty acids 
D) proto-oncogene 
E) R2C2
F)R1C2
G)cAMP
H)phospholipase C
I)protein kinase C (PK
C) 
J)epinephrine
K)oncogene
L)small G proteins

Question 6

How many 7TM membranes are there? What are some of their functions?

Accepted Answer

There are estimated to be thousands of 7

Question 7

What are the two messenger products formed by cleavage of PIP2?

Accepted Answer

A)  diacylglyercol and inositol 1,4,5-triphosphate 
B)  diacylglyercol and inositol 1,3,5-triphosphate 
C)  diacylglyercol and inositol 1,3-diphosphate 
D)  diacylglyercol phosphate and inositol 1,4,5-trisphosphate 
E)  None of the above. 
A)  diacylglyercol and inositol 1,4,5-triphosphate 
B)  diacylglyercol and inositol 1,3,5-triphosphate 
C)  diacylglyercol and inositol 1,3-diphosphate 
D)  diacylglyercol phosphate and inositol 1,4,5-trisphosphate 
E)  None of the above.

Question 8

______________ may be effective anticancer drugs.

Accepted Answer

A)  Monoclonal antibodies against offending receptors 
B)  EGF mimics 
C)  Protein kinase inhibitors 
D)  All of the above. 
E)  Both A and C. 
A)  Monoclonal antibodies against offending receptors 
B)  EGF mimics 
C)  Protein kinase inhibitors 
D)  All of the above. 
E)  Both A and C.

Question 9

Choose the correct answer from the list below. Not all of the answers will be used.
-____________: A gene that leads to the transformation of susceptible cell types into cell types with cancer-like characteristics.

Accepted Answer

A) protein kinase A (PK
A)  
B) calmodulin 
C) fatty acids 
D) proto-oncogene 
E) R2C2
F)R1C2
G)cAMP
H)phospholipase C
I)protein kinase C (PK
C) 
J)epinephrine
K)oncogene
L)small G proteins 
A) protein kinase A (PK
A)  
B) calmodulin 
C) fatty acids 
D) proto-oncogene 
E) R2C2
F)R1C2
G)cAMP
H)phospholipase C
I)protein kinase C (PK
C) 
J)epinephrine
K)oncogene
L)small G proteins

Exam 13: Signal Transduction Pathways

7TM is an abbreviation for ________________ receptors.

Protein kinase A phosphorylates serine and ________________ residues.

Describe the role of phosphoinositol 4,5-bisphosphate (PIP2) in insulin signal transduction.

What steps lead from the activation of a cross-phosphorylated receptor tyrosine kinase to an activated small G protein such as Ras?

Choose the correct answer from the list below. Not all of the answers will be used. -Ras is a member of the ____________ family of proteins.

How many 7TM membranes are there? What are some of their functions?

What are the two messenger products formed by cleavage of PIP2?

______________ may be effective anticancer drugs.

Choose the correct answer from the list below. Not all of the answers will be used. -____________: A gene that leads to the transformation of susceptible cell types into cell types with cancer-like characteristics.

Biochemistry and the Unity of Life

Water, Weak Bonds, and the Generation of Order Out of Chaos

Amino Acids

Protein Three-Dimensional Structure

Techniques in Protein Biochemistry

Basic Concepts of Enzyme Action

Kinetics and Regulation

Mechanisms and Inhibitors

Hemoglobin: an Allosteric Protein

Carbohydrates

Lipids

Membrane Structure and Function

Digestion: Turning a Meal Into Cellular Biochemicals

Metabolism: Basic Concepts and Design

Glycolysis

Gluconeogenesis

Preparation for the Cycle

Harvesting Electrons From the Cycle

The Electron Transport Chain

The Proton-Motive Force

The Light Reactions

The Calvin Cycle

Glycogen Degradation

Glycogen Synthesis

The Pentose Phosphate Pathway

Fatty Acid Degredation

Fatty Acid Synthesis

Lipid Synthesis

Amino Acid Degradation and the Urea Cycle

Amino Acids Synthesis

Nucleotide Metabolism

The Structure of Informational Macromolecules: Dna and Rna

DNA Replication

DNA Repair and Recombination

RNA Synthesis and Regulation in Prokaryotes

Gene Expression in Eukaryotes

RNA Processing in Eukaryotes

The Genetic Code

The Mechanism of Protein Synthesis

Recombinant DNA Techniques

Filters

What are the two messenger products formed by cleavage of PIP₂?