Exam 8: Synaptic Transmission and Neural Integration

Neuropeptides are synthesized in what region of a neuron?

The final integration of postsynaptic potentials that determines whether an action potential is generated occurs within what region of a neuron?

Metabotropic receptor- induced gating of ion channels requires more time to occur because of which of the following?

What enzyme catalyzes breakdown of acetylcholine?

is an amino acid neurotransmitter at excitatory synapses whereas is an amino acid neurotransmitter at inhibitory synapses.

An axoaxonic synapse is unique in its ability to affect neurotransmitter release, but not the action potential.

What happens to the resting membrane potential of - 70 mV when potassium channels close?

Two or more graded potentials originating from different synapses on the same neuron at approximately the same time will cause spatial summation.

Once an action potential reaches the axon terminal, that depolarization stimulates the release of neurotransmitters that can be modulated by other neurons that synapse with the axon terminal. Describe how neurotransmitters are released from the axon terminal and how that response is altered by axoaxonic synapses.

Neurotransmitters can be reused through the process of , where neurotransmitters are transported back across the presynaptic membrane.

What ion directly triggers neurotransmitter release from the presynaptic neuron?

If the resting membrane potential is - 70 mV, which cation will move more frequently through a small cation channel?

Fast excitatory responses not only occur quickly, but they

Fast EPSPs are produced at which of the following types of receptor?

How does temporal summation create an action potential?

All of the following receptor sub- types are ionotropic, EXCEPT

What happens to the resting membrane potential of - 70 mV when channels for an anion with an equilibrium potential of - 80 mV open?

If a membrane is depolarized to +10 mV, which cation will move more frequently through a small cation channel?

What happens to the resting membrane potential of - 70 mV when sodium channels open?

The neurotransmitter for skeletal muscle is acetylcholine which binds to nicotinic receptors on skeletal muscle. Describe the process whereby acetylcholine is synthesized, released, and degraded within the synapse.