Exam 23: Transposition

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_______________ is an enzyme that can synthesize DNA from an RNA template.

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Reverse transcriptase

The recombinases RAG-1 and RAG-2 are expressed in both plasma and memory B-cells.

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False

Hybrid dysgenesis may lead to the formation of new species.

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True

HERVs,human endogenous retroviruses make up about 10-20% of the human genome.

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The loss of bases or gain of bases is common in immunoglobulin gene rearrangement.

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Which of the following transposons does not contain LTRs or inverted repeats at its ends?

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Group II introns are non-LTR retrotransposons that are found only in bacterial cells.

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Which of the following is not necessary for retroviral insertion into the host genome?

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The constant region of an antibody contains the antigen binding domains.

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In ____________transposition both strands of the original DNA move together whereas in _________ transposition one copy of the DNA moves to a new site while one copy stays in the genome.

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Individuals with SCID,severe combined immunodeficiency disease,have defective ________ genes,which cause loss of B-cell and T-cell function.

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In order for P element transfer to happen in Drosophila which of the following situations must occur?

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Antibiotic resistance in bacteria can be transferred using insertion sequences.

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The Ds transposable element of maize cannot transpose on its own because it lacks

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Which of the following is not true concerning immunoglobulin gene recombination signal sequences?

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Insertion sequences are transposable elements that can inactivate genes.

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__________ receptor genes undergo rearrangement in a manor similar to B-cell immunoglobulin genes.

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Transposable elements or _________ are DNA fragments that can move from one organism to another.

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5'-ACCGTAG-GATGCCA-3'is an example of an inverted repeat sequence.

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DNA sequences that resemble normal genes but do not function are called________.

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