Question 1

Under which of the following conditions does TfR mRNA degradation take place?

Accepted Answer

A) conversion of citrate to isocitrate 
B) IRE hairpin loop formation 
C) aconitase apoprotein binding to IRES 
D) low iron concentrations 
E) high iron concentrations 
A) conversion of citrate to isocitrate 
B) IRE hairpin loop formation 
C) aconitase apoprotein binding to IRES 
D) low iron concentrations 
E) high iron concentrations E

Question 2

Dicer is an RNase III-like enzyme that cleaves dsRNA into 50-55 nt fragments.

Accepted Answer

A) True 
 B)False  False

Question 3

If you were to treat mammary gland tissue with prolactin you would expect to see an increase in casein mRNA __________________.

Accepted Answer

stability (or half-life

Question 4

miRNA synthesis involves the cleavage of the double stranded stem portion of a precursor RNA by the enzyme ____________.

Accepted Answer

The answer of miRNA synthesis involves the cleavage of the...

Question 5

Trypanosome mRNA editing occurs in the ______________.

Accepted Answer

The answer of Trypanosome mRNA editing occurs in the ______________....

Question 6

Which of the following enzymes removes extra nucleotides from the 5' ends of pre-tRNA?

Accepted Answer

A) RNase I 
B) RNase II 
C) RNase III 
D) RNase E 
E) RNase P 
A) RNase I 
B) RNase II 
C) RNase III 
D) RNase E 
E) RNase P

Question 7

Which of the following techniques was used by Stuart and colleagues to demonstrate mRNA editing?

Accepted Answer

A) RT-PCR 
B) cDNA cloning 
C) Northern Blot 
D) RNase footprinting 
E) mutation analysis 
A) RT-PCR 
B) cDNA cloning 
C) Northern Blot 
D) RNase footprinting 
E) mutation analysis

Question 8

Processing a pri-miRNA to a mature miRNA is a two-step process.

Accepted Answer

A) True 
 B)False

Question 9

_________ RNA is responsible for RNA interference.

Accepted Answer

The answer of _________ RNA is responsible for RNA interference....

Question 10

rRNA gene transcription occurs in the ______________.

Accepted Answer

The answer of rRNA gene transcription occurs in the ______________....

Question 11

RNA editing by nucleotide deamination can occur in which of the following cell types?

Accepted Answer

A) human brain 
B) HIV infected human cells 
C) red blood cells 
D) Drosophila 
E) All of the choices have RNA editing. 
A) human brain 
B) HIV infected human cells 
C) red blood cells 
D) Drosophila 
E) All of the choices have RNA editing.

Question 12

RNA interference occurs naturally in human cells during

Accepted Answer

A) RNA viral replication. 
B) DNA viral replication. 
C) RNA viral transcription. 
D) DNA viral transcription. 
E) mRNA translation. 
A) RNA viral replication. 
B) DNA viral replication. 
C) RNA viral transcription. 
D) DNA viral transcription. 
E) mRNA translation.

Question 13

Select one of the choices below to indicate whether it is a characteristic of miRNA or siRNA.
-Usually base pair imperfectly with their target mRNA A

Accepted Answer

A) miRNA 
B) siRNA 
A) miRNA 
B) siRNA

Question 14

________-splicing is the process by which exons from different genes are spliced together to form the mature mRNA.

Accepted Answer

The answer of ________-splicing is the process by which exons...

Question 15

Post-transcriptional processing of RNA occurs only in eukaryotic cells.

Accepted Answer

A) True 
 B)False

Question 16

Inactivation of RNase genes involved in tRNA 3'end maturation is lethal to bacterial cells.

Accepted Answer

A) True 
 B)False

Question 17

Flowering plants have two nuclear RNA RNA polymerases,Iv and V,that are not found in animals and fungi.

Accepted Answer

A) True 
 B)False

Question 18

Transposition of transposons is blocked in animal germ cells by a ping-pong and mRNA destruction mechanism involving piRNAs.

Accepted Answer

A) True 
 B)False

Question 19

Which of the following enzymes is not involved in RNA interference?

Accepted Answer

A) Dicer 
B) Slicer 
C) Argonaute 
D) Argonaute2 
E) RNase P 
A) Dicer 
B) Slicer 
C) Argonaute 
D) Argonaute2 
E) RNase P

Question 20

In which of the following organisms is trans-splicing of mRNA known to occur?

Accepted Answer

A) trypanosomes 
B) yeast 
C) bacteria 
D) mammals 
E) plants 
A) trypanosomes 
B) yeast 
C) bacteria 
D) mammals 
E) plants

Exam 16: Rna Processing: Other Post-Transcriptional Events

Under which of the following conditions does TfR mRNA degradation take place?

Dicer is an RNase III-like enzyme that cleaves dsRNA into 50-55 nt fragments.

If you were to treat mammary gland tissue with prolactin you would expect to see an increase in casein mRNA __________________.

miRNA synthesis involves the cleavage of the double stranded stem portion of a precursor RNA by the enzyme ____________.

Trypanosome mRNA editing occurs in the ______________.

Which of the following enzymes removes extra nucleotides from the 5' ends of pre-tRNA?

Which of the following techniques was used by Stuart and colleagues to demonstrate mRNA editing?

Processing a pri-miRNA to a mature miRNA is a two-step process.

_________ RNA is responsible for RNA interference.

rRNA gene transcription occurs in the ______________.

RNA editing by nucleotide deamination can occur in which of the following cell types?

RNA interference occurs naturally in human cells during

Select one of the choices below to indicate whether it is a characteristic of miRNA or siRNA. -Usually base pair imperfectly with their target mRNA A

________-splicing is the process by which exons from different genes are spliced together to form the mature mRNA.

Post-transcriptional processing of RNA occurs only in eukaryotic cells.

Inactivation of RNase genes involved in tRNA 3'end maturation is lethal to bacterial cells.

Flowering plants have two nuclear RNA RNA polymerases,Iv and V,that are not found in animals and fungi.

Transposition of transposons is blocked in animal germ cells by a ping-pong and mRNA destruction mechanism involving piRNAs.

Which of the following enzymes is not involved in RNA interference?

In which of the following organisms is trans-splicing of mRNA known to occur?

A Brief History

The Molecular Nature of Genes

An Introduction to Gene Function

Molecular Cloning Methods

Molecular Tools for Studying Genes and Gene Activity

The Mechanism of Transcription in Bacteria

Operons: Fine Control of Bacterial Transcription

Major Shifts in Bacterial Transcription

Dna-Protein Interactions in Bacteria

Eukaryotic Rna Polymerases and Their Promoters

General Transcription Factors in Eukaryotes

Transcription Activators in Eukaryotes

Chromatin Structure and Its Effect on Transcription

Rna Processing I: Splicing

Rna Processing II: Capping and Polyadenylation

The Mechanism of Translation I: Initiation

The Mechanism of Translation II: Elongation and Termination

Ribosomes and Transfer Rna

Dna Replication,damage and Repair

Dna Replication II: Detailed Mechanism

Homologous Recombination

Transposition

Introduction to Genomics: Dna Sequencing on a Genomic Scale

Genomics II: Functional Genomics,proteomics and Bioinformatics

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