Exam 18: The Mechanism of Translation II: Elongation and Termination

The hydrolysis of _________ is necessary for the release of EF-G from the ribosome,which significantly accelerates translocation.

Which of the following are the three naturally occurring stop codons?

Which of the following molecules does not resemble a tRNA molecule?

Amber mutation suppressors are _____________ molecules.

Mitochondrial mRNAs contain codons that don't conform to the universal genetic code.

EF-Tu is one of the most abundant proteins in the cell.

Peptidyl transferase activity is located in the _________ subunit of the ribosome.

Which of the following antibiotics does not inhibit protein synthesis by binding to the ribosome?

Pyrrolysine and ____________ are examples of unusual amino acids that can be incorporated into proteins using stop codons.

Misfolding of nascent proteins can occur when inappropriate _______________ regions of the protein interact with each other.

During translation elongation each translocation step moves the mRNA _______ through the ribosome.

The genetic code is composed of codons where each codon contains ____________ bases and encodes for ___________ amino acid.

The correct folding of proteins in the cell is accomplished with the help of __________ __________.

Noller,Mankin,and colleagues,using KSP particle data and reconstitution experiments,concluded that the minimal component necessary for peptidyl transferase activity is the 23S rRNA.

A transversion is a mutation in the genetic code that changes a purine to a pyrimidine.

Misfolded proteins can be toxic to cells and lead to serious disease in humans.Which of the following diseases is caused by a misfolded protein?

There are only 64 codons in the genetic code.

Wobble base pairing can occur between tRNA and the third base in the mRNA codon.

Translation termination release factors are tRNA molecules that have anticodons complimentary to the three stop codons.

The antibiotic puromycin resembles a(n)___________ and can bind to the A site of the ribosome.