Exam 18: Regulation of Gene Expression

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Use the following information to answer the questions below. Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. -If she moves the repressor gene (lac I), along with its promoter, to a position at some several thousand base pairs away from its normal position, which will you expect to occur?

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E

Use the following information to answer the questions below. A researcher has arrived at a method to prevent gene expression from Drosophila embryonic genes. The following questions assume that he is using this method. -The researcher in question measures the amount of new polypeptide production in embryos from 2-8 hours following fertilization and the results show a steady and significant rise in polypeptide concentration over that time. The researcher concludes that

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C

Embryonic lethal mutations result in

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D

Use the following information to answer the questions below. A researcher found a method she could use to manipulate and quantify phosphorylation and methylation in embryonic cells in culture. -One of her colleagues suggested she try increased methylation of C nucleotides in a mammalian system. Which of the following results would she most likely see?

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In positive control of several sugar-metabolism-related operons, the catabolite activator protein (CAP)binds to DNA to stimulate transcription. What causes an increase in CAP?

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In eukaryotes, general transcription factors

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Cell differentiation always involves

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The bicoid gene product is normally localized to the anterior end of the embryo. If large amounts of the product were injected into the posterior end as well, which of the following would occur?

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Altering patterns of gene expression in prokaryotes would most likely serve the organism's survival in which of the following ways?

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Use the following figure to answer the questions below. Use the following figure to answer the questions below.    -Where would B be located in the cell? -Where would B be located in the cell?

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Use the following information to answer the questions below. Epstein Bar Virus (EBV) causes most of us to have an episode of sore throat and swollen glands during early childhood. If we first become exposed to the virus during our teen years, however, EBV causes the syndrome we know as mononucleosis. However, in special circumstances, the same virus can be carcinogenic. -In areas of the world where malaria is endemic, notably in sub-Saharan Africa, EBV can cause Burkitt's lymphoma in children, which is usually associated with large tumours of the jaw. Which of the following is consistent with these findings?

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Which of the following is most likely to have a small protein called ubiquitin attached to it?

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Use the following information to answer the questions below. A researcher found a method she could use to manipulate and quantify phosphorylation and methylation in embryonic cells in culture. -In one set of experiments using this procedure in Drosophila, she was readily successful in increasing phosphorylation of amino acids adjacent to methylated amino acids in histone tails. Which of the following results would she most likely see?

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The term epigenetics refers to

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The role of a metabolite that controls a repressible operon is to

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   Drosophila larvae (wt) showing segmentation and anterior-posterior axis. Refer to the image above to answer the following questions. -What would happen if the maternal nurse cells were to have a mutant bicoid gene? Drosophila larvae (wt) showing segmentation and anterior-posterior axis. Refer to the image above to answer the following questions. -What would happen if the maternal nurse cells were to have a mutant bicoid gene?

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Which of the following, when taken up by the cell, binds to the repressor so that the repressor no longer binds to the operator?

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The functioning of enhancers is an example of

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Use the following figure to answer the questions below. Use the following figure to answer the questions below.    -What is the significance of C and D? -What is the significance of C and D?

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Which of the following statements describes proto-oncogenes?

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