Exam 25: Genomics II: Functional Genomics,proteomics and Bioinformatics

Which of the following prcoesses allows scientists to determine the expression patterns (temporal and spatial)of many genes at once?

"Knocking out" genes is laborious.A simpler alternative to 'knock down' gene expression is called _____ ____________.

Class II promoters can be identified using ChIP-chip analysis with an anti-TAF1 antibody.

To find enhancers whose protein partners are unknown,one can look for non-coding sequences that are highly conserved between moderately related species or absolutely conserved between closely related species.

Which of the following techniques was developed by Velculescu and colleagues to determine which genes are expressed in a given tissue?

Genomic sequence information can be applied to study which of the following?

DNA microarrays can be used to study

The underlying strategy of the technique _________ is to synthesize short cDNAs,or tags,from all the mRNAs in a cell,and then to link these tags together in clones that can be sequences to learn the nature of the tags,and therefore the nature of the genes expressed in the cell.

Which of the following is not a technique that can be used to study protein-protein interactions?

Most proteins do not function in isolation,but collaborate with other proteins.