Exam 15: Rna Processing II: Capping and Polyadenylation

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The 5' cap of mRNA has no effect on the translatability of the mRNA.

(True/False)
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Uncapped mRNA is much more stable then capped mRNA.

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Please put the following steps of Cap synthesis in the correct order.(1)N7 of the capping guanine is methylated.(2)The terminal phosphate is removed from the pre-mRNA.(3)A capping GMP is added to the pre-mRNA.(4)The 2'O-methyl group of the penultimate nucleotide is methylated.

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The human vaccinia virus replicates in the _________ of cells and therefore must carry with it its own capping enzymes.

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Poly(A)tails are added to the 5' end of the mRNA molecule.

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The fact that actinomycin D does not inhibit polyadenylation supports the fact that

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Although snRNA U1 functions in the nucleus,it receives a 5' cap to enhance its

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Cytoplasmic ___________ remove (A)s from the poly(A)tail.

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Polyadenylation is not required for efficient transport of mRNA out of the nucleus.

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Once the poly(A)tail is added to the mRNA it is very difficult to remove.

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The CTD domain of which subunit of RNA Polymerase II has been shown to be involved in pre-mRNA processing?

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