Question 1

An example of DNA-binding protein that contains a zinc finger motif is Gal4.

Accepted Answer

A) True 
 B)False

Question 2

An experiment is planned to look at the effect of blocking the thyroid hormone receptor.Which of the following is a good technique to employ?

Accepted Answer

A) phosphorylation 
B) methylation 
C) ubiquitination 
D) sumoylation 
E) all of the choices are correct. 
A) phosphorylation 
B) methylation 
C) ubiquitination 
D) sumoylation 
E) all of the choices are correct.

Question 3

Type II receptors reside in the cytoplasm where they bind to hormone ligands.

Accepted Answer

A) True 
 B)False

Question 4

The glucocorticoid receptor is activated by binding to

Accepted Answer

A) its hormone ligand then moving to the nucleus. 
B) its hormone ligand protein partner and then moving to the nucleus. 
C) its hormone partner in the nucleus. 
D) DNA and then to its hormone ligand. 
E) None of the choices are correct. 
A) its hormone ligand then moving to the nucleus. 
B) its hormone ligand protein partner and then moving to the nucleus. 
C) its hormone partner in the nucleus. 
D) DNA and then to its hormone ligand. 
E) None of the choices are correct.

Question 5

The DNA-binding and activation domains of activator proteins are independent molecules.

Accepted Answer

A) True 
 B)False

Question 6

Which of the following are typical features of transcriptional activators?

Accepted Answer

A) transcription-activation domain 
B) DNA-binding domain 
C) kinase domain 
D) transcription-activation domain and DNA-binding domain 
E) transcription-activation domain and kinase domain 
A) transcription-activation domain 
B) DNA-binding domain 
C) kinase domain 
D) transcription-activation domain and DNA-binding domain 
E) transcription-activation domain and kinase domain

Question 7

Heterodimers are sometimes found in the dimerization domain of transcription activators.

Accepted Answer

A) True 
 B)False

Question 8

Which of the following is a target site for GAL4?

Accepted Answer

A) UASG 
B) CCAAT 
C) GCAAT 
D) UASG and CCAAT 
E) CCAAT and GCAAT 
A) UASG 
B) CCAAT 
C) GCAAT 
D) UASG and CCAAT 
E) CCAAT and GCAAT

Question 9

All of the following are true regarding homeodomains except

Accepted Answer

A) they contain about 60 amino acids. 
B) they resemble prokaryotic helix-turn-helix domains. 
C) they are a class of DNA-binding proteins. 
D) they may be involved in the regulation of development. 
E) they are repressors. 
A) they contain about 60 amino acids. 
B) they resemble prokaryotic helix-turn-helix domains. 
C) they are a class of DNA-binding proteins. 
D) they may be involved in the regulation of development. 
E) they are repressors.

Question 10

Transcription activators help to boost transcription by recruiting RNA polymerase to promoters.

Accepted Answer

A) True 
 B)False

Question 11

Which of the following are found in bZip and HLH domains?

Accepted Answer

A) leucine zipper 
B) helix-loop-helix regions 
C) zinc fingers 
D) leucine zipper and helix-loop-helix regions 
E) helix-loop-helix regions and zinc fingers 
A) leucine zipper 
B) helix-loop-helix regions 
C) zinc fingers 
D) leucine zipper and helix-loop-helix regions 
E) helix-loop-helix regions and zinc fingers

An example of DNA-binding protein that contains a zinc finger motif is Gal4.

An experiment is planned to look at the effect of blocking the thyroid hormone receptor.Which of the following is a good technique to employ?

Type II receptors reside in the cytoplasm where they bind to hormone ligands.

The glucocorticoid receptor is activated by binding to

The DNA-binding and activation domains of activator proteins are independent molecules.

Which of the following are typical features of transcriptional activators?

Heterodimers are sometimes found in the dimerization domain of transcription activators.

Which of the following is a target site for GAL4?

All of the following are true regarding homeodomains except

Transcription activators help to boost transcription by recruiting RNA polymerase to promoters.

Which of the following are found in bZip and HLH domains?

A Brief History

The Molecular Nature of Genes

An Introduction to Gene Function

Molecular Cloning Methods

Molecular Tools for Studying Genes and Gene Activity

The Mechanism of Transcription in Bacteria

Operons: Fine Control of Bacterial Transcription

Major Shifts in Bacterial Transcription

Dna-Protein Interactions in Bacteria

Eukaryotic Rna Polymerases and Their Promoters

General Transcription Factors in Eukaryotes

Chromatin Structure and Its Effect on Transcription

Rna Processing I: Splicing

Rna Processing II: Capping and Polyadenylation

Rna Processing: Other Post-Transcriptional Events

The Mechanism of Translation I: Initiation

The Mechanism of Translation II: Elongation and Termination

Ribosomes and Transfer Rna

Dna Replication,damage and Repair

Dna Replication II: Detailed Mechanism

Homologous Recombination

Transposition

Introduction to Genomics: Dna Sequencing on a Genomic Scale

Genomics II: Functional Genomics,proteomics and Bioinformatics

Filters

Exam 12: Transcription Activators in Eukaryotes

An example of DNA-binding protein that contains a zinc finger motif is Gal4.

An experiment is planned to look at the effect of blocking the thyroid hormone receptor.Which of the following is a good technique to employ?

Type II receptors reside in the cytoplasm where they bind to hormone ligands.

The glucocorticoid receptor is activated by binding to

The DNA-binding and activation domains of activator proteins are independent molecules.

Which of the following are typical features of transcriptional activators?

Heterodimers are sometimes found in the dimerization domain of transcription activators.

Which of the following is a target site for GAL4?

All of the following are true regarding homeodomains except

Transcription activators help to boost transcription by recruiting RNA polymerase to promoters.

Which of the following are found in bZip and HLH domains?

A Brief History

The Molecular Nature of Genes

An Introduction to Gene Function

Molecular Cloning Methods

Molecular Tools for Studying Genes and Gene Activity

The Mechanism of Transcription in Bacteria

Operons: Fine Control of Bacterial Transcription

Major Shifts in Bacterial Transcription

Dna-Protein Interactions in Bacteria

Eukaryotic Rna Polymerases and Their Promoters

General Transcription Factors in Eukaryotes

Chromatin Structure and Its Effect on Transcription

Rna Processing I: Splicing

Rna Processing II: Capping and Polyadenylation

Rna Processing: Other Post-Transcriptional Events

The Mechanism of Translation I: Initiation

The Mechanism of Translation II: Elongation and Termination

Ribosomes and Transfer Rna

Dna Replication,damage and Repair

Dna Replication II: Detailed Mechanism

Homologous Recombination

Transposition

Introduction to Genomics: Dna Sequencing on a Genomic Scale

Genomics II: Functional Genomics,proteomics and Bioinformatics

Filters