Exam 7: Cellular Respiration: Harvesting Chemical Energy

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Racker and Stoeckenius used synthetic phospholipid membrane vesicles that contained a light-activated protein pump and ATP synthase to test Mitchell's chemiosmotic hypothesis. What was the conclusion of this experiment?

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B

During which stages of cellular respiration is CO2released?

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E

It has been thought that many diseases now associated with aging are related to malfunctioning mitochondria. Why are the mitochondria so important to all cells?

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A

What powers ATP synthase directly?

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When triglycerides are hydrolyzed, they are broken down into glycerol and fatty acids. The fatty acids are further broken down into two-carbon fragments in a process called fatty acid oxidation. At which pathway do these fragments enter respiration?

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At the end of cellular respiration, oxygen combines with electrons of a very low energy level. How are the specific properties of oxygen beneficial to the organism that uses it as a final electron acceptor?

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For every glucose molecule that goes through cellular respiration, how many carbon atoms are fully oxidized to CO2in the citric acid cycle?

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Suppose we hypothesize that potato plants use uncoupling proteins (UCPs) in a similar way as mammals. What would be the evidence to support this hypothesis?

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Two mobile electron carriers that are important for the electron transport chain are cytochrome c and coenzyme Q.

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The final product of glycolysis is ____.

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About 10-20% of patients with Leigh Syndrome, a mitochondrial disease, have a mutation in MT-ATP6, a gene that codes for ATP synthase. These patients often experience high levels of _____ in their cells due to an increase in levels of pyruvate that are unable to convert to acetyl-CoA.

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Where is ATP synthase located in non-photosynthetic eukaryotes?

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   Refer to the accompanying figure. In what part of the mitochondrion or cell do the following steps of cellular respiration take place? Not all choices will be used; some may be used more than once.
Refer to the accompanying figure. In what part of the mitochondrion or cell do the following steps of cellular respiration take place? Not all choices will be used; some may be used more than once.
pyruvate oxidation
cytosol
glycolysis
inner mitochondrial membrane
electron transport chain
outer mitochondrial membrane
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pyruvate oxidation
cytosol
glycolysis
inner mitochondrial membrane
electron transport chain
outer mitochondrial membrane
ATP synthesis
intermembrane compartment
citric acid cycle
matrix
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What is the fate of CoA after it delivers an acetyl group into the citric acid cycle?

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The process of glucose biosynthesis is called gluconeogenesis.

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What is the function of NADH and FADH2?

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How do cyanide and carbon monoxide affect cellular respiration?

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What supplies the electrons for oxidative phosphorylation?

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How does cellular respiration differ in prokaryotes and eukaryotes?

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Match the following processes with the correct products.
pyruvate, ATP, NADH , H+, and H2O
pyruvate oxidation
lactate and NAD+
the citric acid cycle
CO2, NADH, FADH2, ATP, H+, and CoA
glycolysis
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pyruvate, ATP, NADH , H+, and H2O
pyruvate oxidation
lactate and NAD+
the citric acid cycle
CO2, NADH, FADH2, ATP, H+, and CoA
glycolysis
NAD+, FAD, and ATP
fermentation
acetyl-coA, CO2 ,NADH, and H+
oxidative phosphorylation
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