Question 1

N-linked glycosylation occurs when carbohydrate groups are added to

Accepted Answer

A)  The side chain NH2 of asparagine 
B)  The side chain NH2 of lysine 
C)  The side chain N of histidine 
D)  The side chain N of N-acetylglucosamine 
E)  The side chain NH2 of serine 
A)  The side chain NH2 of asparagine 
B)  The side chain NH2 of lysine 
C)  The side chain N of histidine 
D)  The side chain N of N-acetylglucosamine 
E)  The side chain NH2 of serine A

Question 2

All amino acids contain

Accepted Answer

A)  An amino group (-NH 2) 
B)  An asymmetric carbon 
C)  A carboxyl group (-COOH) 
D)  A, B and C 
E)  A and C 
A)  An amino group (-NH 2) 
B)  An asymmetric carbon 
C)  A carboxyl group (-COOH) 
D)  A, B and C 
E)  A and C E

Question 3

O-linked glycosylation occurs when carbohydrate groups are added to

Accepted Answer

A)  The hydroxyl group of threonine 
B)  The hydroxyl group of hydroxyproline 
C)  The hydroxyl group of serine 
D)  The hydroxyl group of tyrosine 
E)  Both A and C are correct 
A)  The hydroxyl group of threonine 
B)  The hydroxyl group of hydroxyproline 
C)  The hydroxyl group of serine 
D)  The hydroxyl group of tyrosine 
E)  Both A and C are correct E

Question 4

An example of a non-polar amino acid is

Accepted Answer

A)  Tyrosine 
B)  Histidine 
C)  Threonine 
D)  Glutamic acid 
E)  Leucine 
A)  Tyrosine 
B)  Histidine 
C)  Threonine 
D)  Glutamic acid 
E)  Leucine

Question 5

Phosphorylation of proteins typically occurs at which of the following amino acids?

Accepted Answer

A)  Aspartic acid 
B)  Serine 
C)  Tryptophan 
D)  Phenylalanine 
E)  Proline 
A)  Aspartic acid 
B)  Serine 
C)  Tryptophan 
D)  Phenylalanine 
E)  Proline

Question 6

Non-polar amino acids include all of the following EXCEPT

Accepted Answer

A)  Tryptophan 
B)  Phenylalanine 
C)  Leucine 
D)  Lysine 
E)  Valine 
A)  Tryptophan 
B)  Phenylalanine 
C)  Leucine 
D)  Lysine 
E)  Valine

Question 7

Which of the following is NOT one of the non-covalent interactions that stabilize protein structure?

Accepted Answer

A)  Hydrogen bonding 
B)  Electrostatic attraction/repulsion 
C)  Hydrophobic interactions 
D)  Quantum tunneling 
E)  Steric hindrance 
A)  Hydrogen bonding 
B)  Electrostatic attraction/repulsion 
C)  Hydrophobic interactions 
D)  Quantum tunneling 
E)  Steric hindrance

Question 8

Proteins can be anchored to membranes by

Accepted Answer

A)  Covalent attachment of the protein to GPI (glycosyl phosphatidyl inositol) 
B)  Covalent attachment to retinal in membranes 
C)  Linkage to myristic acid through the carboxyl terminal COOH 
D)  Linkage to myristic acid through cysteine 
E)  Linkage to farnesyl through the N-terminus 
A)  Covalent attachment of the protein to GPI (glycosyl phosphatidyl inositol) 
B)  Covalent attachment to retinal in membranes 
C)  Linkage to myristic acid through the carboxyl terminal COOH 
D)  Linkage to myristic acid through cysteine 
E)  Linkage to farnesyl through the N-terminus

Question 9

Which of the following amino acids is most hydrophobic?

Accepted Answer

A)  Lysine 
B)  Aspartic acid 
C)  Serine 
D)  Tyrosine 
E)  Isoleucine 
A)  Lysine 
B)  Aspartic acid 
C)  Serine 
D)  Tyrosine 
E)  Isoleucine

Question 10

An example of a polar amino acid is

Accepted Answer

A)  Tryptophan 
B)  Arginine 
C)  Aspartic acid 
D)  Serine 
E)  Phenylalanine 
A)  Tryptophan 
B)  Arginine 
C)  Aspartic acid 
D)  Serine 
E)  Phenylalanine

Question 11

Peptide bonds form on the ribosome between

Accepted Answer

A)  The am ino group of a lysine R chain and the carboxyl group of an aspartic R chain 
B)  The carboxyl group on the carboxyl terminus of the growing chain and the amino
group of the next am ino acid 
C)  The amino group on the amino terminus of the growing chain and the carboxyl group of the
next amino acid 
D)  Amino and carboxyl groups of adjacent amino acids in the interior of the polypeptide 
E)  The alpha carbon and the R group 
A)  The am ino group of a lysine R chain and the carboxyl group of an aspartic R chain 
B)  The carboxyl group on the carboxyl terminus of the growing chain and the amino
group of the next am ino acid 
C)  The amino group on the amino terminus of the growing chain and the carboxyl group of the
next amino acid 
D)  Amino and carboxyl groups of adjacent amino acids in the interior of the polypeptide 
E)  The alpha carbon and the R group

Question 12

"Hydrophobicity" of an amino acid describes

Accepted Answer

A)  Thenum ber of hydrocarbons in its R group 
B)  Its ability to dissolve in water 
C)  Its preference for non-polar solvents over water 
D)  The number of polar groups on the amino acid 
E)  The number of charged groups on the amino acid 
A)  Thenum ber of hydrocarbons in its R group 
B)  Its ability to dissolve in water 
C)  Its preference for non-polar solvents over water 
D)  The number of polar groups on the amino acid 
E)  The number of charged groups on the amino acid

Question 13

Post-translational modifications of proteins includes

Accepted Answer

A)  Elongation 
B)  Replication 
C)  Transcription 
D)  Proteolytic cleavage 
E)  Initiation 
A)  Elongation 
B)  Replication 
C)  Transcription 
D)  Proteolytic cleavage 
E)  Initiation

Question 14

The final three-dimensional structure of proteins is important because

Accepted Answer

A)  The pictures are awesome 
B)  Protein function occurs through interactions on the surfaces of the proteins 
C)  They are not two-dimensional structures 
D)  Amino acids nearby in the 3D structure are usually not adjacent in the primary structure 
E)  The structure is dictated by the function 
A)  The pictures are awesome 
B)  Protein function occurs through interactions on the surfaces of the proteins 
C)  They are not two-dimensional structures 
D)  Amino acids nearby in the 3D structure are usually not adjacent in the primary structure 
E)  The structure is dictated by the function

Question 15

Arginine is an example of a

Accepted Answer

A)  Acidic amino acid 
B)  Basic amino acid 
C)  Non-polar amino acid 
D)  Polar amino acid 
E)  Aromatic amino acid 
A)  Acidic amino acid 
B)  Basic amino acid 
C)  Non-polar amino acid 
D)  Polar amino acid 
E)  Aromatic amino acid

Question 16

Chemical post-translational modifications include all of the following EXCEPT

Accepted Answer

A)  Phosphorylation 
B)  Methylation 
C)  Ubiquitinylation 
D)  Acetylation 
E)  Transesterification 
A)  Phosphorylation 
B)  Methylation 
C)  Ubiquitinylation 
D)  Acetylation 
E)  Transesterification

Question 17

The linear sequence of am ino acids that make up a single polypeptide chain is called its

Accepted Answer

A)  Primary structure 
B)  Secondary structure 
C)  Tertiary structure 
D)  Quarternary structure 
E)  Code 
A)  Primary structure 
B)  Secondary structure 
C)  Tertiary structure 
D)  Quarternary structure 
E)  Code

Exam 8: Protein Structure

N-linked glycosylation occurs when carbohydrate groups are added to

All amino acids contain

O-linked glycosylation occurs when carbohydrate groups are added to

An example of a non-polar amino acid is

Phosphorylation of proteins typically occurs at which of the following amino acids?

Non-polar amino acids include all of the following EXCEPT

Which of the following is NOT one of the non-covalent interactions that stabilize protein structure?

Proteins can be anchored to membranes by

Which of the following amino acids is most hydrophobic?

An example of a polar amino acid is

Peptide bonds form on the ribosome between

"Hydrophobicity" of an amino acid describes

Post-translational modifications of proteins includes

The final three-dimensional structure of proteins is important because

Arginine is an example of a

Chemical post-translational modifications include all of the following EXCEPT

The linear sequence of am ino acids that make up a single polypeptide chain is called its

Physical Foundations Ii: Electrical Force Potential Capacitance and Current

Chemical Foundations I: Chemical Energy and Intermolecular Forces

Chemical Foundations Ii: Concentration and Kinetics

Diffusion

Electrochemical Potential and Free Energy

Cell Structure

Dna and Protein Synthesis

Biological Membranes

Passive Transport and Facilitated Diffusion

Active Transport: Pumps and Exchangers

Osmosis and Osmotic Pressure

Cell Signaling

ATP Production I: Glycolysis

Atp Production Ii: Tca Cycle and Oxidative Phosphorylation

Atp Production Iii: Fatty Acid Oxidation and Amino Acid Oxidation

Origin of the Membrane Potential

The Action Potential

Propagation of the Action Potential

Skeletal Muscle Mechanics

Contractile Mechanisms in Skeletal Muscle

Neuromuscular Junction and Ec Coupling

Muscle Energetics Fatigue and Training

Smooth Muscle

Organization of the Nervous System

Cells Synapses and Neurotransmitters

Cutaneous Sensory Systems

Spinal Reflexes

Balance and Control of Movement

the Chemical Senses

Hearing

Vision

Autonomic Nervous System

Overview of the Cv System and Blood

Plasma and Red Blood Cells

White Blood Cells and Inflammation

The Heart As a Pump

Cellular Basis of Cardiac Contractility

the Cardiac Function Curve

Vascular Function: Hemodynamics

Microcirculation and Solute Exchange

Regulation of Perfusion

Integration of Cardiac Output and Venous Return

Regulation of Arterial Pressure

Mechanics of Breathing

Lung Volumes and Airway Resistance

Gas Exchange in the Lung

Oxygen and Carbon Dioxide Transport

Acid Base Physiology I Bicarbonate Buffers and Respiratory Compensation

Control of Ventilation

Anatomy and Renal Overview

Glomerular Filtration

Tubular Reabsorption and Secretion

Concentration and Dilution of Urine

Mouth and Esophagus

The Stomach

Intestinal and Colonic Motility

Pancreatic and Biliary Secretion

Digestion and Absorption of the Macronutrients

Energy Balance and Regulation of Food Intake

General Principles of Endocrinology

Hypothalamus and Pituitary Gland

The Thyroid Gland