Question 1

Which of the following is not an assumption when calculating volumes of distribution using the Fick dilution principle?

Accepted Answer

A)  The concentration of the solute is homogeneous among all its volume of distribution. 
B)  The amount of solute is known at the time of sampling of the volume in which it is distributed. 
C)  The volume in which the solute is distributed is well mixed. 
D)  The solute’s concentration can be determined. 
E)  The solute is small. 
A)  The concentration of the solute is homogeneous among all its volume of distribution. 
B)  The amount of solute is known at the time of sampling of the volume in which it is distributed. 
C)  The volume in which the solute is distributed is well mixed. 
D)  The solute’s concentration can be determined. 
E)  The solute is small. E

Question 2

Suppose that the glucose concentration in normal plasma is 5.0 mM. If the gram-molecular weight is 180 g mol-1 and the normal plasma volume is 4 L , what is the mass of all of the glucose that is contained in all of the plasma?

Accepted Answer

A)  20 g 
B)  20 mol 
C)  20 mm ol 
D)  3.6 g 
E)  0.36 g 
A)  20 g 
B)  20 mol 
C)  20 mm ol 
D)  3.6 g 
E)  0.36 g D

Question 3

The gram molecular weight of urea, CO (NH2 )2 is about

Accepted Answer

A)  48 g mol-1 
B)  48 daltons 
C)  48 g 
D)  60 g mol-1 
E)  180 g mol-1 
A)  48 g mol-1 
B)  48 daltons 
C)  48 g 
D)  60 g mol-1 
E)  180 g mol-1 D

Question 4

For an experiment, we weighed out 18 g of NaCl and dissolved it into a final volume of 500 mL with water. The atomic weight of Na is 22.99 and Cl is 35.45. What is the molar concentration of NaCl
in the final solution?

Accepted Answer

A)  1.57 M 
B)  1.02 M 
C)  0.62 M 
D)  0.15 M 
E)  0.31 M 
A)  1.57 M 
B)  1.02 M 
C)  0.62 M 
D)  0.15 M 
E)  0.31 M

Question 5

You have a 0.1 M solution of ATP and take 6.25 mL of it to add to a 25 mL volumetric flask, along with some other solutions, which is then brought up to volume to make a stock solution. You then add 1 mL of that stock solution to a reaction bath that has a total final volume, including the 1 mL of stock solution, of 5 mL. W hat is the ATP concentration in the final reaction bath?

Accepted Answer

A)  0.025 M 
B)  0.05 M 
C)  0.02 M 
D)  0.005 M 
E)  Cannot be calculated from the information given. 
A)  0.025 M 
B)  0.05 M 
C)  0.02 M 
D)  0.005 M 
E)  Cannot be calculated from the information given.

Question 6

The glucose concentration in plasma is typically 100 mg% , meaning 100 mg in 100 mL of plasma. The gram molecular weight of glucose is 180 g mol-1. W hat is the molar concentration of this plasma glucose?

Accepted Answer

A)  50 mM 
B)  56 mM 
C)  5.0 mM 
D)  5 .6 mM 
E)  1.8 mM 
A)  50 mM 
B)  56 mM 
C)  5.0 mM 
D)  5 .6 mM 
E)  1.8 mM

Question 7

The Michaelis-Menten equation is written as

Accepted Answer

A)  V = Vmax S / (KMS + 1) 
B)  V = Vmax S / KM 
C)  V = Vmax S 
D)  V = Vmax S / (KM + S) 
E)  None of the above 
A)  V = Vmax S / (KMS + 1) 
B)  V = Vmax S / KM 
C)  V = Vmax S 
D)  V = Vmax S / (KM + S) 
E)  None of the above

Question 8

If the double-reciprocal plot of an enzyme is linear, the intercept on the abscissa (vertical axis) is

Accepted Answer

A)  Vmax 
B)  KM 
C)  - 1 / K M 
D)  1 / V max 
E)  KM / Vmax 
A)  Vmax 
B)  KM 
C)  - 1 / K M 
D)  1 / V max 
E)  KM / Vmax

Question 9

Enzymes catalyze reactions by

Accepted Answer

A)  speeding up binding of substrate 
B)  Speeding up dissociation of product 
C)  Lowering the activation energy 
D)  Increasing the energy available for the reaction 
E)  Changing the equilibrium constant for the reaction 
A)  speeding up binding of substrate 
B)  Speeding up dissociation of product 
C)  Lowering the activation energy 
D)  Increasing the energy available for the reaction 
E)  Changing the equilibrium constant for the reaction

Question 10

You dissolved 100 g of a material with a molecule weight of 5.5 kDa in 1 L of solution. Its molar concentration is

Accepted Answer

A)  18 nM 
B)  18 µ M 
C)  1.8 mM 
D)  18 mM 
E)  18 M 
A)  18 nM 
B)  18 µ M 
C)  1.8 mM 
D)  18 mM 
E)  18 M

Question 11

For the reaction A + B →C, the reverse rate constant has the units

Accepted Answer

A)  s-1 
B)  M s-1 
C)  M-1 s-1 
D)  Ms 
E)  M-1s 
A)  s-1 
B)  M s-1 
C)  M-1 s-1 
D)  Ms 
E)  M-1s

Question 12

You took 0.5 m L of concentration HCl, at 11.5 M, and added it to a 100mL volumetric flask, and then added water to the mark. The concentration of HCl in the final solution is

Accepted Answer

A)  0.5 M 
B)  0.0575 M 
C)  0.115 M 
D)  1.15 M 
E)  0.575 M 
A)  0.5 M 
B)  0.0575 M 
C)  0.115 M 
D)  1.15 M 
E)  0.575 M

Exam 3: Chemical Foundations Ii: Concentration and Kinetics

Which of the following is not an assumption when calculating volumes of distribution using the Fick dilution principle?

Suppose that the glucose concentration in normal plasma is 5.0 mM. If the gram-molecular weight is 180 g mol-1 and the normal plasma volume is 4 L , what is the mass of all of the glucose that is contained in all of the plasma?

The gram molecular weight of urea, CO (NH2 )2 is about

For an experiment, we weighed out 18 g of NaCl and dissolved it into a final volume of 500 mL with water. The atomic weight of Na is 22.99 and Cl is 35.45. What is the molar concentration of NaCl in the final solution?

The glucose concentration in plasma is typically 100 mg% , meaning 100 mg in 100 mL of plasma. The gram molecular weight of glucose is 180 g mol-1. W hat is the molar concentration of this plasma glucose?

The Michaelis-Menten equation is written as

If the double-reciprocal plot of an enzyme is linear, the intercept on the abscissa (vertical axis) is

Enzymes catalyze reactions by

You dissolved 100 g of a material with a molecule weight of 5.5 kDa in 1 L of solution. Its molar concentration is

For the reaction A + B →C, the reverse rate constant has the units

You took 0.5 m L of concentration HCl, at 11.5 M, and added it to a 100mL volumetric flask, and then added water to the mark. The concentration of HCl in the final solution is

Physical Foundations Ii: Electrical Force Potential Capacitance and Current

Chemical Foundations I: Chemical Energy and Intermolecular Forces

Diffusion

Electrochemical Potential and Free Energy

Cell Structure

Dna and Protein Synthesis

Protein Structure

Biological Membranes

Passive Transport and Facilitated Diffusion

Active Transport: Pumps and Exchangers

Osmosis and Osmotic Pressure

Cell Signaling

ATP Production I: Glycolysis

Atp Production Ii: Tca Cycle and Oxidative Phosphorylation

Atp Production Iii: Fatty Acid Oxidation and Amino Acid Oxidation

Origin of the Membrane Potential

The Action Potential

Propagation of the Action Potential

Skeletal Muscle Mechanics

Contractile Mechanisms in Skeletal Muscle

Neuromuscular Junction and Ec Coupling

Muscle Energetics Fatigue and Training

Smooth Muscle

Organization of the Nervous System

Cells Synapses and Neurotransmitters

Cutaneous Sensory Systems

Spinal Reflexes

Balance and Control of Movement

the Chemical Senses

Hearing

Vision

Autonomic Nervous System

Overview of the Cv System and Blood

Plasma and Red Blood Cells

White Blood Cells and Inflammation

The Heart As a Pump

Cellular Basis of Cardiac Contractility

the Cardiac Function Curve

Vascular Function: Hemodynamics

Microcirculation and Solute Exchange

Regulation of Perfusion

Integration of Cardiac Output and Venous Return

Regulation of Arterial Pressure

Mechanics of Breathing

Lung Volumes and Airway Resistance

Gas Exchange in the Lung

Oxygen and Carbon Dioxide Transport

Acid Base Physiology I Bicarbonate Buffers and Respiratory Compensation

Control of Ventilation

Anatomy and Renal Overview

Glomerular Filtration

Tubular Reabsorption and Secretion

Concentration and Dilution of Urine

Mouth and Esophagus

The Stomach

Intestinal and Colonic Motility

Pancreatic and Biliary Secretion

Digestion and Absorption of the Macronutrients

Energy Balance and Regulation of Food Intake

General Principles of Endocrinology

Hypothalamus and Pituitary Gland

The Thyroid Gland

The Endocrine Pancreas

The Adrenal Cortex

The Adrenal Medulla

The Calcitropic Hormones

Calcium and Phosphorus Homeostasis Ii

Female Reproductive Physiology

The gram molecular weight of urea, CO (NH₂ )₂ is about