Question 1

Myoglobin in muscle cells

Accepted Answer

A)  Stores oxygen 
B)  Binds Ca2+ 
C)  Helps carry oxygen to the mitochondria 
D)  Helps relax m uscle 
E)  Both A and C are true 
A)  Stores oxygen 
B)  Binds Ca2+ 
C)  Helps carry oxygen to the mitochondria 
D)  Helps relax m uscle 
E)  Both A and C are true A

Question 2

In the figure, which curve represents the normal hemoglobin oxygen dissociation curve?

Accepted Answer

A)  A 
B)  B 
C)  C 
D)  D 
E)  E 
A)  A 
B)  B 
C)  C 
D)  D 
E)  E C

Question 3

Which of the following DOES NOT shift the hem oglo bin oxygen dissociation curve to the right?

Accepted Answer

A)  Increased temp erature 
B)  Increased PO2 
C)  Decreased pH 
D)  Increased PCO2 
E)  Increased 2,3-diphosphoglycerate (2,3 DPG) 
A)  Increased temp erature 
B)  Increased PO2 
C)  Decreased pH 
D)  Increased PCO2 
E)  Increased 2,3-diphosphoglycerate (2,3 DPG) B

Question 4

Positive cooperativity mak es the oxygen disso ciation curve

Accepted Answer

A)  Biphasic 
B)  Sigmoid-shaped 
C)  Parabolic 
D)  Hyperbolic 
E)  Linear 
A)  Biphasic 
B)  Sigmoid-shaped 
C)  Parabolic 
D)  Hyperbolic 
E)  Linear

Question 5

Oxygen consum ption occurs

Accepted Answer

A)  At the cell mem brane 
B)  Mainly in the endoplasmic reticulum 
C)  Mainly in the liver 
D)  Mainly in the brain 
E)  Mainly in the mitochondria 
A)  At the cell mem brane 
B)  Mainly in the endoplasmic reticulum 
C)  Mainly in the liver 
D)  Mainly in the brain 
E)  Mainly in the mitochondria

Question 6

Oxygen binding to hemoglobin

Accepted Answer

A)  occurs with a stoichiometry of 4 O2 molecules per Fe-containing heme group 
B)  shows negative cooperativity 
C)  Is similar in form to its binding to myoglobin binding except it binds tighter to hemoglobin 
D)  is generally saturated at PaO2 of 40 mm Hg 
E)  none of the above 
A)  occurs with a stoichiometry of 4 O2 molecules per Fe-containing heme group 
B)  shows negative cooperativity 
C)  Is similar in form to its binding to myoglobin binding except it binds tighter to hemoglobin 
D)  is generally saturated at PaO2 of 40 mm Hg 
E)  none of the above

Question 7

Among the following, the highest PO2 is found in

Accepted Answer

A)  Air 
B)  Moist tracheal air 
C)  Alveolar air 
D)  Arterial Blood 
E)  Tissues 
A)  Air 
B)  Moist tracheal air 
C)  Alveolar air 
D)  Arterial Blood 
E)  Tissues

Question 8

The per cent of the net delivery of CO2 from tissue to lungs that is carried by HCO3- is about

Accepted Answer

A)  0 % 
B)  5% 
C)  10% 
D)  40% 
E)  85% 
A)  0 % 
B)  5% 
C)  10% 
D)  40% 
E)  85%

Question 9

Increasing the CO2 in the tissues causes

Accepted Answer

A)  a shift in the Hb (hemoglobin) saturation curve to the left 
B)  an upward shift in the Hb saturation curve 
C)  Hb to bind O2 less strongly 
D)  An increased pH 
E)  none of the above 
A)  a shift in the Hb (hemoglobin) saturation curve to the left 
B)  an upward shift in the Hb saturation curve 
C)  Hb to bind O2 less strongly 
D)  An increased pH 
E)  none of the above

Question 10

Chloride

Accepted Answer

A)  Moves into RBCs in the tissues and out of RBCs in the lungs 
B)  Moves into RBCs in the tissues and in the lungs 
C)  Moves out of RBCs in the tissues and into the RBCs in the lungs 
D)  Moves out of RBCs in the tissues and in the lungs 
E)  Moves across the RBC m embrane but unrelated to its position in the circulation 
A)  Moves into RBCs in the tissues and out of RBCs in the lungs 
B)  Moves into RBCs in the tissues and in the lungs 
C)  Moves out of RBCs in the tissues and into the RBCs in the lungs 
D)  Moves out of RBCs in the tissues and in the lungs 
E)  Moves across the RBC m embrane but unrelated to its position in the circulation

Question 11

Am ong the following, the highest PCO2 is found in

Accepted Answer

A)  The air 
B)  Moist tracheal air 
C)  Alveolar air 
D)  Arterial Blood 
E)  Tissues 
A)  The air 
B)  Moist tracheal air 
C)  Alveolar air 
D)  Arterial Blood 
E)  Tissues

Question 12

Positive cooperativity means

Accepted Answer

A)  Binding at one site increases the affinity of binding at a second vacant site 
B)  Binding at a site on the protein is independent of occupancy of other sites. 
C)  Protein molecules bind together to allow oxygen binding 
D)  Protein-protein interaction is necessary for oxygen binding 
E)  The slope of the dissociation curve is m axim al at lowest PaO2 
A)  Binding at one site increases the affinity of binding at a second vacant site 
B)  Binding at a site on the protein is independent of occupancy of other sites. 
C)  Protein molecules bind together to allow oxygen binding 
D)  Protein-protein interaction is necessary for oxygen binding 
E)  The slope of the dissociation curve is m axim al at lowest PaO2

Question 13

Shifting the hemoglobin oxygen dissociation curve to the right

Accepted Answer

A) Is the same as reducing the affinity of hemoglobin for oxygen 
B) Means that less oxygen is bound at a given PO2 
C) Makes it easier to unload oxygen in the tissues 
D) Means that hemoglobin binds oxygen less tightly 
E) All of the above 
A) Is the same as reducing the affinity of hemoglobin for oxygen 
B) Means that less oxygen is bound at a given PO2 
C) Makes it easier to unload oxygen in the tissues 
D) Means that hemoglobin binds oxygen less tightly 
E) All of the above

Question 14

The normal saturation of hemoglobin in arterial blood is

Accepted Answer

A)  100% 
B)  95% 
C)  75% 
D)  46% 
E)  40% 
A)  100% 
B)  95% 
C)  75% 
D)  46% 
E)  40%

Exam 48: Oxygen and Carbon Dioxide Transport

Myoglobin in muscle cells

In the figure, which curve represents the normal hemoglobin oxygen dissociation curve?

Which of the following DOES NOT shift the hem oglo bin oxygen dissociation curve to the right?

Positive cooperativity mak es the oxygen disso ciation curve

Oxygen consum ption occurs

Oxygen binding to hemoglobin

Among the following, the highest PO2 is found in

The per cent of the net delivery of CO2 from tissue to lungs that is carried by HCO3- is about

Increasing the CO2 in the tissues causes

Chloride

Am ong the following, the highest PCO2 is found in

Positive cooperativity means

Shifting the hemoglobin oxygen dissociation curve to the right

The normal saturation of hemoglobin in arterial blood is

Physical Foundations Ii: Electrical Force Potential Capacitance and Current

Chemical Foundations I: Chemical Energy and Intermolecular Forces

Chemical Foundations Ii: Concentration and Kinetics

Diffusion

Electrochemical Potential and Free Energy

Cell Structure

Dna and Protein Synthesis

Protein Structure

Biological Membranes

Passive Transport and Facilitated Diffusion

Active Transport: Pumps and Exchangers

Osmosis and Osmotic Pressure

Cell Signaling

ATP Production I: Glycolysis

Atp Production Ii: Tca Cycle and Oxidative Phosphorylation

Atp Production Iii: Fatty Acid Oxidation and Amino Acid Oxidation

Origin of the Membrane Potential

The Action Potential

Propagation of the Action Potential

Skeletal Muscle Mechanics

Contractile Mechanisms in Skeletal Muscle

Neuromuscular Junction and Ec Coupling

Muscle Energetics Fatigue and Training

Smooth Muscle

Organization of the Nervous System

Cells Synapses and Neurotransmitters

Cutaneous Sensory Systems

Spinal Reflexes

Balance and Control of Movement

the Chemical Senses

Hearing

Vision

Autonomic Nervous System

Overview of the Cv System and Blood

Plasma and Red Blood Cells

White Blood Cells and Inflammation

The Heart As a Pump

Cellular Basis of Cardiac Contractility

the Cardiac Function Curve

Vascular Function: Hemodynamics

Microcirculation and Solute Exchange

Regulation of Perfusion

Integration of Cardiac Output and Venous Return

Regulation of Arterial Pressure

Mechanics of Breathing

Lung Volumes and Airway Resistance

Gas Exchange in the Lung

Acid Base Physiology I Bicarbonate Buffers and Respiratory Compensation

Control of Ventilation

Anatomy and Renal Overview

Glomerular Filtration

Tubular Reabsorption and Secretion

Concentration and Dilution of Urine

Mouth and Esophagus

The Stomach

Intestinal and Colonic Motility

Pancreatic and Biliary Secretion

Digestion and Absorption of the Macronutrients

Energy Balance and Regulation of Food Intake

General Principles of Endocrinology

Hypothalamus and Pituitary Gland

The Thyroid Gland

The Endocrine Pancreas

The Adrenal Cortex

The Adrenal Medulla

Among the following, the highest P_O2 is found in

The per cent of the net delivery of CO₂ from tissue to lungs that is carried by HCO₃- is about

Increasing the C_O2 in the tissues causes

Am ong the following, the highest P_CO2is found in