Question 1

What is the fundamental physiologic manifestation of anemia?

Accepted Answer

A)  Hypotension 
B)  Hyperesthesia 
C)  Hypoxia 
D)  Ischemia 
A)  Hypotension 
B)  Hyperesthesia 
C)  Hypoxia 
D)  Ischemia C

Question 2

Which condition resulting from untreated pernicious anemia (PA)is fatal?

Accepted Answer

A)  Brain hypoxia 
B)  Liver hypoxia 
C)  Heart failure 
D)  Renal failure 
A)  Brain hypoxia 
B)  Liver hypoxia 
C)  Heart failure 
D)  Renal failure C

Question 3

Which statement best describes a Schilling test?

Accepted Answer

A)  Administration of radioactive cobalamin and the measurement of its excretion in the urine to test for vitamin B12 deficiency 
B)  Measurement of antigen-antibody immune complexes in the blood to test for hemolytic anemia 
C)  Measurement of serum ferritin and total iron-binding capacity in the blood to test for iron deficiency anemia 
D)  Administration of folate and measurement in 2 hours of its level in a blood sample to test for folic acid deficiency anemia. 
A)  Administration of radioactive cobalamin and the measurement of its excretion in the urine to test for vitamin B12 deficiency 
B)  Measurement of antigen-antibody immune complexes in the blood to test for hemolytic anemia 
C)  Measurement of serum ferritin and total iron-binding capacity in the blood to test for iron deficiency anemia 
D)  Administration of folate and measurement in 2 hours of its level in a blood sample to test for folic acid deficiency anemia. A

Question 4

What are the clinical manifestations of folate deficiency anemia? (Select all that apply.)

Accepted Answer

A)  Constipation 
B)  Flatulence 
C)  Dysphagia 
D)  Stomatitis 
E)  Cheilosis 
A)  Constipation 
B)  Flatulence 
C)  Dysphagia 
D)  Stomatitis 
E)  Cheilosis

Question 5

Sideroblastic anemia can occasionally result from an autosomal recessive transmission inherited from which relative?

Accepted Answer

A)  Mother 
B)  Father 
C)  Grandfather 
D)  Grandmother 
A)  Mother 
B)  Father 
C)  Grandfather 
D)  Grandmother

Question 6

A 2000 ml blood loss will produce which assessment finding? (Select all that apply.)

Accepted Answer

A)  Air hunger 
B)  Normal blood pressure in the supine position 
C)  Rapid thready pulse 
D)  Cold clammy skin 
E)  lactic acidosis 
A)  Air hunger 
B)  Normal blood pressure in the supine position 
C)  Rapid thready pulse 
D)  Cold clammy skin 
E)  lactic acidosis

Question 7

What term is used to describe the capacity of some erythrocytes to vary in size,especially in relationship to some anemias?

Accepted Answer

A)  Poikilocytosis 
B)  Isocytosis 
C)  Anisocytosis 
D)  Microcytosis 
A)  Poikilocytosis 
B)  Isocytosis 
C)  Anisocytosis 
D)  Microcytosis

Question 8

Which conditions are generally included in the symptoms of pernicious anemia (PA)? (Select all that apply.)

Accepted Answer

A)  Weakness 
B)  Weight gain 
C)  Low hemoglobin 
D)  Paresthesias 
E)  Low hematocrit 
A)  Weakness 
B)  Weight gain 
C)  Low hemoglobin 
D)  Paresthesias 
E)  Low hematocrit

Question 9

Match the phrases with the corresponding terms.Options may be used more than once.
-Pernicious anemia

Accepted Answer

A) Normocytic-normochromic anemia 
B) Microcytic-hypochromic anemia 
C) Macrocytic-normochromic anemia 
A) Normocytic-normochromic anemia 
B) Microcytic-hypochromic anemia 
C) Macrocytic-normochromic anemia

Question 10

An allogenic bone marrow transplantation remains the preferred method for treating which anemia?

Accepted Answer

A)  Polycythemia vera 
B)  Aplastic 
C)  Sideroblastic 
D)  Anemia of chronic disease (AC
D)  
A)  Polycythemia vera 
B)  Aplastic 
C)  Sideroblastic 
D)  Anemia of chronic disease (AC
D)

Question 11

Considering iron replacement therapy prescribed for iron deficiency anemia,who is likely to require long-term daily maintenance dosage?

Accepted Answer

A)  A woman who has not yet experienced menopause 
B)  A teenager who is involved in strenuous athletics 
C)  A middle-aged man who smokes two packs of cigarettes a day 
D)  An older person demonstrating signs of dementia 
A)  A woman who has not yet experienced menopause 
B)  A teenager who is involved in strenuous athletics 
C)  A middle-aged man who smokes two packs of cigarettes a day 
D)  An older person demonstrating signs of dementia

Question 12

Which statement is true regarding warm autoimmune hemolytic anemia?

Accepted Answer

A)  Warm autoimmune hemolytic anemia occurs primarily in men. 
B)  It is self-limiting and rarely produces hemolysis. 
C)  Erythrocytes are bound to macrophages and sequestered in the spleen. 
D)  Immunoglobulin M coats erythrocytes and binds them to receptors on monocytes. 
A)  Warm autoimmune hemolytic anemia occurs primarily in men. 
B)  It is self-limiting and rarely produces hemolysis. 
C)  Erythrocytes are bound to macrophages and sequestered in the spleen. 
D)  Immunoglobulin M coats erythrocytes and binds them to receptors on monocytes.

Question 13

In aplastic anemia (AA),pancytopenia develops as a result of which of the following?

Accepted Answer

A)  Suppression of erythropoietin to produce adequate amounts of erythrocytes 
B)  Suppression of the bone marrow to produce adequate amounts of erythrocytes, leukocytes, and thrombocytes 
C)  Lack of DNA to form sufficient quantities of erythrocytes, leukocytes, and thrombocytes 
D)  Lack of stem cells to form sufficient quantities of leukocytes 
A)  Suppression of erythropoietin to produce adequate amounts of erythrocytes 
B)  Suppression of the bone marrow to produce adequate amounts of erythrocytes, leukocytes, and thrombocytes 
C)  Lack of DNA to form sufficient quantities of erythrocytes, leukocytes, and thrombocytes 
D)  Lack of stem cells to form sufficient quantities of leukocytes

Question 14

The paresthesia that occurs in vitamin B₁₂ deficiency anemia is a result of which of the following?

Accepted Answer

A)  Reduction in acetylcholine receptors in the postsynaptic nerves 
B)  Myelin degeneration in the spinal cord 
C)  Destruction of myelin in peripheral nerves 
D)  Altered function of neurons in the parietal lobe 
A)  Reduction in acetylcholine receptors in the postsynaptic nerves 
B)  Myelin degeneration in the spinal cord 
C)  Destruction of myelin in peripheral nerves 
D)  Altered function of neurons in the parietal lobe

Question 15

Deficiencies in folate and vitamin B₁₂ alter the synthesis of which of the following?

Accepted Answer

A)  RNA 
B)  Cell membrane 
C)  DNA 
D)  Mitochondria 
A)  RNA 
B)  Cell membrane 
C)  DNA 
D)  Mitochondria

Question 16

Continued therapy of pernicious anemia (PA)generally lasts how long?

Accepted Answer

A)  6 to 8 weeks 
B)  8 to 12 months 
C)  Until the iron level is normal 
D)  The rest of one's life 
A)  6 to 8 weeks 
B)  8 to 12 months 
C)  Until the iron level is normal 
D)  The rest of one's life

Question 17

Which statement is true regarding the physical manifestations of vitamin B₁₂ deficiency anemia?

Accepted Answer

A)  Vitamin B12 deficiency anemia seldom results in neurologic symptoms. 
B)  The chances of a cure are good with appropriate treatment. 
C)  The condition is reversible in 75% of the cases. 
D)  Symptoms are a result of demyelination. 
A)  Vitamin B12 deficiency anemia seldom results in neurologic symptoms. 
B)  The chances of a cure are good with appropriate treatment. 
C)  The condition is reversible in 75% of the cases. 
D)  Symptoms are a result of demyelination.

Question 18

Which anemia produces small,pale erythrocytes?

Accepted Answer

A)  Folic acid 
B)  Hemolytic 
C)  Iron deficiency 
D)  Pernicious 
A)  Folic acid 
B)  Hemolytic 
C)  Iron deficiency 
D)  Pernicious

Question 19

Match the phrases with the corresponding terms.Options may be used more than once.
-Aplastic anemia

Accepted Answer

A) Normocytic-normochromic anemia 
B) Microcytic-hypochromic anemia 
C) Macrocytic-normochromic anemia 
A) Normocytic-normochromic anemia 
B) Microcytic-hypochromic anemia 
C) Macrocytic-normochromic anemia

Question 20

After a person has a subtotal gastrectomy for chronic gastritis,which type of anemia will result?

Accepted Answer

A)  Iron deficiency 
B)  Aplastic 
C)  Folic acid 
D)  Pernicious 
A)  Iron deficiency 
B)  Aplastic 
C)  Folic acid 
D)  Pernicious

Exam 28: Alterations of Erythrocyte Function

What is the fundamental physiologic manifestation of anemia?

Which condition resulting from untreated pernicious anemia (PA)is fatal?

Which statement best describes a Schilling test?

What are the clinical manifestations of folate deficiency anemia? (Select all that apply.)

Sideroblastic anemia can occasionally result from an autosomal recessive transmission inherited from which relative?

A 2000 ml blood loss will produce which assessment finding? (Select all that apply.)

What term is used to describe the capacity of some erythrocytes to vary in size,especially in relationship to some anemias?

Which conditions are generally included in the symptoms of pernicious anemia (PA)? (Select all that apply.)

Match the phrases with the corresponding terms.Options may be used more than once. -Pernicious anemia

An allogenic bone marrow transplantation remains the preferred method for treating which anemia?

Considering iron replacement therapy prescribed for iron deficiency anemia,who is likely to require long-term daily maintenance dosage?

Which statement is true regarding warm autoimmune hemolytic anemia?

In aplastic anemia (AA),pancytopenia develops as a result of which of the following?

The paresthesia that occurs in vitamin B₁₂ deficiency anemia is a result of which of the following?

Deficiencies in folate and vitamin B₁₂ alter the synthesis of which of the following?

Continued therapy of pernicious anemia (PA)generally lasts how long?

Which statement is true regarding the physical manifestations of vitamin B₁₂ deficiency anemia?

Which anemia produces small,pale erythrocytes?

Match the phrases with the corresponding terms.Options may be used more than once. -Aplastic anemia

After a person has a subtotal gastrectomy for chronic gastritis,which type of anemia will result?

Cellular Biology

Altered Cellular and Tissue Biology

The Cellular Environment: Fluids and Electrolytes, Acids and Bases

Genes and Genetic Diseases

Genes, Environment-Lifestyle, and Common Diseases

Epigenetics and Disease

Innate Immunity: Inflammation

Adaptive Immunity

Alterations in Immunity and Inflammation

Infection

Stress and Disease

Cancer Biology

Cancer Epidemiology

Cancer in Children

Structure and Function of the Neurologic System

Pain, Temperature Regulation, Sleep, and Sensory Function

Alterations in Cognitive Systems,Cerebral Hemodynamics,and Motor Function

Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction

Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

Alterations of Neurologic Function in Children

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

Structure and Function of the Reproductive Systems

Alterations of the Female Reproductive System

Alterations of the Male Reproductive System

Sexually Transmitted Infections

Structure and Function of the Hematologic System

Alterations of Leukocyte, Lymphoid, and Hemostatic Function

Alterations of Hematologic Function in Children

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Alterations of Pulmonary Function in Children

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function

Alterations of Musculoskeletal Function in Children

Structure, Function, and Disorders of the Integument

Alterations of the Integument in Children

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children

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