Question 1

Which cells of the dermis secrete connective tissue matrix?

Accepted Answer

A)  Macrophages 
B)  Mast cells 
C)  Fibroblasts 
D)  Histiocytes 
A)  Macrophages 
B)  Mast cells 
C)  Fibroblasts 
D)  Histiocytes

Question 2

A small (less than 1 cm)lesion with regular edges and bristlelike hairs with a color change that can range from skin tones to light brown characterize which form of nevus?

Accepted Answer

A)  Junctional 
B)  Epidermal 
C)  Intradermal 
D)  Compound 
A)  Junctional 
B)  Epidermal 
C)  Intradermal 
D)  Compound

Question 3

Which skin disorder begins with a single lesion that is circular,demarcated,and salmon pink,measures approximately 3 to 4 cm in diameter,and is usually located on the trunk?

Accepted Answer

A)  Lichen planus 
B)  Pityriasis rosea 
C)  Psoriasis 
D)  Acne rosacea 
A)  Lichen planus 
B)  Pityriasis rosea 
C)  Psoriasis 
D)  Acne rosacea

Question 4

Scleroderma is associated with _________________.

Accepted Answer

A)  X-linked recessive gene 
B)  X-linked dominant gene 
C)  Virus 
D)  Autoantibodies 
A)  X-linked recessive gene 
B)  X-linked dominant gene 
C)  Virus 
D)  Autoantibodies

Question 5

Match the descriptions of the skin lesions with the disorder where it is found.
-Varicella (chickenpox),herpes zoster (shingles)

Accepted Answer

A) Elevated, firm circumscribed area less than 1 cm in diameter 
B) Elevated, firm, and rough lesion with a flat top surface greater than 1 cm in diameter 
C) Flat circumscribed area that is less than 1 cm in diameter 
D) Elevated irregular-shaped area of cutaneous edema; solid and transient with a variable diameter 
E) Elevated circumscribed, superficial lesion filled with serous fluid, less than 1 cm in diameter 
A) Elevated, firm circumscribed area less than 1 cm in diameter 
B) Elevated, firm, and rough lesion with a flat top surface greater than 1 cm in diameter 
C) Flat circumscribed area that is less than 1 cm in diameter 
D) Elevated irregular-shaped area of cutaneous edema; solid and transient with a variable diameter 
E) Elevated circumscribed, superficial lesion filled with serous fluid, less than 1 cm in diameter

Question 6

Which cells of the dermis release histamine and play a role in the hypersensitivity reactions of the skin?

Accepted Answer

A)  Histiocytes 
B)  Fibroblasts 
C)  Mast cells 
D)  Macrophages 
A)  Histiocytes 
B)  Fibroblasts 
C)  Mast cells 
D)  Macrophages

Question 7

Which immunoglobulin is found in skin biopsy with immunofluorescent observation of people with discoid lupus erythematosus?

Accepted Answer

A)  Immunoglobulin A (Ig
A)  
B)  Immunoglobulin E (Ig
E)  
C)  Immunoglobulin G (IgG) 
D)  Immunoglobulin M (IgM) 
A)  Immunoglobulin A (Ig
A)  
B)  Immunoglobulin E (Ig
E)  
C)  Immunoglobulin G (IgG) 
D)  Immunoglobulin M (IgM)

Question 8

The alteration of which gene is associated with basal cell carcinoma?

Accepted Answer

A)  myc 
B)  TP53 
C)  src 
D)  Ras 
A)  myc 
B)  TP53 
C)  src 
D)  Ras

Question 9

Which statements are true regarding a nevus? (Select all that apply.)

Accepted Answer

A)  A nevus is an aggregation of melanocytes 
B)  Nevi begin to form at the ages of 3 to 5 years. 
C)  Nevi are characterized by irregular borders. 
D)  Nevi share a relationship with melanoma. 
E)  Nevi always warrant being removed. 
A)  A nevus is an aggregation of melanocytes 
B)  Nevi begin to form at the ages of 3 to 5 years. 
C)  Nevi are characterized by irregular borders. 
D)  Nevi share a relationship with melanoma. 
E)  Nevi always warrant being removed.

Question 10

Match the descriptions of the skin lesions with the disorder where it is found.
-Nevus (flat mole)

Accepted Answer

A) Elevated, firm circumscribed area less than 1 cm in diameter 
B) Elevated, firm, and rough lesion with a flat top surface greater than 1 cm in diameter 
C) Flat circumscribed area that is less than 1 cm in diameter 
D) Elevated irregular-shaped area of cutaneous edema; solid and transient with a variable diameter 
E) Elevated circumscribed, superficial lesion filled with serous fluid, less than 1 cm in diameter 
A) Elevated, firm circumscribed area less than 1 cm in diameter 
B) Elevated, firm, and rough lesion with a flat top surface greater than 1 cm in diameter 
C) Flat circumscribed area that is less than 1 cm in diameter 
D) Elevated irregular-shaped area of cutaneous edema; solid and transient with a variable diameter 
E) Elevated circumscribed, superficial lesion filled with serous fluid, less than 1 cm in diameter

Question 11

What name is given to a benign proliferation of basal cells that produces smooth or warty elevated lesions on the chest,back,and face that are tan or waxy,yellow,flesh-colored,or dark brown to black?

Accepted Answer

A)  Basal keratosis 
B)  Seborrheic keratosis 
C)  Keratoacanthoma 
D)  Actinic keratosis 
A)  Basal keratosis 
B)  Seborrheic keratosis 
C)  Keratoacanthoma 
D)  Actinic keratosis

Question 12

What medical term is used to identify an inflammatory disorder of the skin that is often considered synonymous with dermatitis and characterized by pruritus with lesions that have an indistinct border?

Accepted Answer

A)  Eczema 
B)  Psoriasis 
C)  Atopic dermatitis 
D)  Pityriasis rosea 
A)  Eczema 
B)  Psoriasis 
C)  Atopic dermatitis 
D)  Pityriasis rosea

Question 13

Which inflammatory mediators are active in frostbite? (Select all that apply.)

Accepted Answer

A)  Leukotrienes 
B)  Histamine 
C)  Prostaglandins 
D)  Bradykinin 
E)  Thromboxanes 
A)  Leukotrienes 
B)  Histamine 
C)  Prostaglandins 
D)  Bradykinin 
E)  Thromboxanes

Question 14

Which statements are true regarding Kaposi sarcoma? (Select all that apply.)

Accepted Answer

A)  South America has been the site of the endemic form of Kaposi sarcoma. 
B)  Kaposi sarcoma is a vascular malignancy. 
C)  It is associated with drug-induced immunosuppression. 
D)  Kaposi sarcoma is associated with acquired immunodeficiency syndrome (AIDS). 
E)  Presentation of the classic form of Kaposi sarcoma is observed on the lower legs of older men. 
A)  South America has been the site of the endemic form of Kaposi sarcoma. 
B)  Kaposi sarcoma is a vascular malignancy. 
C)  It is associated with drug-induced immunosuppression. 
D)  Kaposi sarcoma is associated with acquired immunodeficiency syndrome (AIDS). 
E)  Presentation of the classic form of Kaposi sarcoma is observed on the lower legs of older men.

Question 15

Which receptors of the sympathetic nervous system regulate heat loss through the skin?

Accepted Answer

A)  Cholinergic 
B)  ß-Adrenergic 
C)  a-Adrenergic 
D)  Anticholinergic 
A)  Cholinergic 
B)  ß-Adrenergic 
C)  a-Adrenergic 
D)  Anticholinergic

Question 16

Which gland releases secretions that are important in thermoregulation and cooling of the body through evaporation?

Accepted Answer

A)  Sebaceous 
B)  Apocrine 
C)  Eccrine 
D)  Exocrine 
A)  Sebaceous 
B)  Apocrine 
C)  Eccrine 
D)  Exocrine

Question 17

Match the descriptions of the skin lesions with the disorder where it is found.
-Urticaria,allergic reaction

Accepted Answer

A) Elevated, firm circumscribed area less than 1 cm in diameter 
B) Elevated, firm, and rough lesion with a flat top surface greater than 1 cm in diameter 
C) Flat circumscribed area that is less than 1 cm in diameter 
D) Elevated irregular-shaped area of cutaneous edema; solid and transient with a variable diameter 
E) Elevated circumscribed, superficial lesion filled with serous fluid, less than 1 cm in diameter 
A) Elevated, firm circumscribed area less than 1 cm in diameter 
B) Elevated, firm, and rough lesion with a flat top surface greater than 1 cm in diameter 
C) Flat circumscribed area that is less than 1 cm in diameter 
D) Elevated irregular-shaped area of cutaneous edema; solid and transient with a variable diameter 
E) Elevated circumscribed, superficial lesion filled with serous fluid, less than 1 cm in diameter

Question 18

Which cell is thought to be the progenitor cell of Kaposi sarcoma?

Accepted Answer

A)  Endothelial 
B)  Keratinocyte 
C)  Melanocyte 
D)  Exothelial 
A)  Endothelial 
B)  Keratinocyte 
C)  Melanocyte 
D)  Exothelial

Question 19

What clinical manifestations do allergic contact and stasis dermatitis have in common?

Accepted Answer

A)  Petechiae and hyperpigmentation 
B)  Edema and vesicular lesions 
C)  Scaling and crusting of lesions 
D)  Erythema and pruritus 
A)  Petechiae and hyperpigmentation 
B)  Edema and vesicular lesions 
C)  Scaling and crusting of lesions 
D)  Erythema and pruritus

Question 20

What is the purpose of administering ibuprofen to individuals being treated for frostbite?

Accepted Answer

A)  Treating fever 
B)  Preventing plate aggregation 
C)  Reducing pain 
D)  Inhibiting prostaglandins 
A)  Treating fever 
B)  Preventing plate aggregation 
C)  Reducing pain 
D)  Inhibiting prostaglandins

Exam 46: Structure, Function, and Disorders of the Integument

Which cells of the dermis secrete connective tissue matrix?

A small (less than 1 cm)lesion with regular edges and bristlelike hairs with a color change that can range from skin tones to light brown characterize which form of nevus?

Which skin disorder begins with a single lesion that is circular,demarcated,and salmon pink,measures approximately 3 to 4 cm in diameter,and is usually located on the trunk?

Scleroderma is associated with _________________.

Match the descriptions of the skin lesions with the disorder where it is found. -Varicella (chickenpox),herpes zoster (shingles)

Which cells of the dermis release histamine and play a role in the hypersensitivity reactions of the skin?

Which immunoglobulin is found in skin biopsy with immunofluorescent observation of people with discoid lupus erythematosus?

The alteration of which gene is associated with basal cell carcinoma?

Which statements are true regarding a nevus? (Select all that apply.)

Match the descriptions of the skin lesions with the disorder where it is found. -Nevus (flat mole)

What name is given to a benign proliferation of basal cells that produces smooth or warty elevated lesions on the chest,back,and face that are tan or waxy,yellow,flesh-colored,or dark brown to black?

What medical term is used to identify an inflammatory disorder of the skin that is often considered synonymous with dermatitis and characterized by pruritus with lesions that have an indistinct border?

Which inflammatory mediators are active in frostbite? (Select all that apply.)

Which statements are true regarding Kaposi sarcoma? (Select all that apply.)

Which receptors of the sympathetic nervous system regulate heat loss through the skin?

Which gland releases secretions that are important in thermoregulation and cooling of the body through evaporation?

Match the descriptions of the skin lesions with the disorder where it is found. -Urticaria,allergic reaction

Which cell is thought to be the progenitor cell of Kaposi sarcoma?

What clinical manifestations do allergic contact and stasis dermatitis have in common?

What is the purpose of administering ibuprofen to individuals being treated for frostbite?

Cellular Biology

Altered Cellular and Tissue Biology

The Cellular Environment: Fluids and Electrolytes, Acids and Bases

Genes and Genetic Diseases

Genes, Environment-Lifestyle, and Common Diseases

Epigenetics and Disease

Innate Immunity: Inflammation

Adaptive Immunity

Alterations in Immunity and Inflammation

Infection

Stress and Disease

Cancer Biology

Cancer Epidemiology

Cancer in Children

Structure and Function of the Neurologic System

Pain, Temperature Regulation, Sleep, and Sensory Function

Alterations in Cognitive Systems,Cerebral Hemodynamics,and Motor Function

Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction

Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

Alterations of Neurologic Function in Children

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

Structure and Function of the Reproductive Systems

Alterations of the Female Reproductive System

Alterations of the Male Reproductive System

Sexually Transmitted Infections

Structure and Function of the Hematologic System

Alterations of Erythrocyte Function

Alterations of Leukocyte, Lymphoid, and Hemostatic Function

Alterations of Hematologic Function in Children

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Alterations of Pulmonary Function in Children

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function

Alterations of Musculoskeletal Function in Children

Alterations of the Integument in Children

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children

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