Question 1

Immunoglobulin E (IgE)is associated with which type of hypersensitivity reaction?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
A)  I 
B)  II 
C)  III 
D)  IV

Question 2

Exposure to which of the following could result in a type IV hypersensitivity reaction? (Select all that apply.)

Accepted Answer

A)  Poison ivy 
B)  Neomycin 
C)  Dairy products 
D)  Nickel 
E)  Detergents 
A)  Poison ivy 
B)  Neomycin 
C)  Dairy products 
D)  Nickel 
E)  Detergents

Question 3

In which primary immune deficiency is there a partial-to-complete absence of T-cell immunity?

Accepted Answer

A)  Bruton disease 
B)  DiGeorge syndrome 
C)  Reticular dysgenesis 
D)  Adenosine deaminase deficiency 
A)  Bruton disease 
B)  DiGeorge syndrome 
C)  Reticular dysgenesis 
D)  Adenosine deaminase deficiency

Question 4

When soluble antigens from infectious agents enter circulation,tissue damage is a result of:

Accepted Answer

A)  Complement-mediated cell lysis 
B)  Phagocytosis by macrophages 
C)  Phagocytosis in the spleen 
D)  Neutrophil granules and toxic oxygen products 
A)  Complement-mediated cell lysis 
B)  Phagocytosis by macrophages 
C)  Phagocytosis in the spleen 
D)  Neutrophil granules and toxic oxygen products

Question 5

A type IV hypersensitivity reaction causes which result?

Accepted Answer

A)  Antibodies coating mast cells by binding to receptors that signal its degranulation, followed by the discharge of preformed mediators 
B)  Antibodies binding to soluble antigens that were released into body fluids and the immune complexes being deposited in the tissues 
C)  Lymphokine-producing Th1 cells directly attacking and destroying cellular targets 
D)  Antibodies binding to the antigen on the cell surface 
A)  Antibodies coating mast cells by binding to receptors that signal its degranulation, followed by the discharge of preformed mediators 
B)  Antibodies binding to soluble antigens that were released into body fluids and the immune complexes being deposited in the tissues 
C)  Lymphokine-producing Th1 cells directly attacking and destroying cellular targets 
D)  Antibodies binding to the antigen on the cell surface

Question 6

A person with type O blood is likely to have high titers of which anti-antibodies?

Accepted Answer

A)  A 
B)  B 
C)  A and B 
D)  O 
A)  A 
B)  B 
C)  A and B 
D)  O

Question 7

Which statement is true concerning an atopic individual?

Accepted Answer

A)  They tend to produce less IgE. 
B)  They tend to produce more Fc receptors. 
C)  They tend to attract very few mast cells. 
D)  They tend to produce very high levels of IgM. 
A)  They tend to produce less IgE. 
B)  They tend to produce more Fc receptors. 
C)  They tend to attract very few mast cells. 
D)  They tend to produce very high levels of IgM.

Question 8

When a tuberculin skin test is positive,the hard center and erythema surrounding the induration are a result of which of the following? (Select all that apply.)

Accepted Answer

A)  Histamine 
B)  T lymphocytes 
C)  Immune complexes 
D)  Products of complement 
E)  Macrophages 
A)  Histamine 
B)  T lymphocytes 
C)  Immune complexes 
D)  Products of complement 
E)  Macrophages

Question 9

Which class of immunoglobulins forms isohemagglutinins?

Accepted Answer

A)  IgA 
B)  IgE 
C)  IgG 
D)  IgM 
A)  IgA 
B)  IgE 
C)  IgG 
D)  IgM

Question 10

Which component of the immune system is deficient in individuals with infections caused by viruses,fungi,or yeast?

Accepted Answer

A)  Natural killer cells 
B)  Macrophages 
C)  B cells 
D)  T cells 
A)  Natural killer cells 
B)  Macrophages 
C)  B cells 
D)  T cells

Question 11

Considering the effects of nutritional deficiencies on the immune system,severe deficits in calories and protein lead to deficiencies in the formation of which immune cells?

Accepted Answer

A)  B cells 
B)  T cells 
C)  Natural killer cells 
D)  Neutrophils 
A)  B cells 
B)  T cells 
C)  Natural killer cells 
D)  Neutrophils

Question 12

Hypersensitivity is best defined as a(an):

Accepted Answer

A)  Disturbance in the immunologic tolerance of self-antigens 
B)  Immunologic reaction of one person to the tissue of another person 
C)  Altered immunologic response to an antigen that results in disease 
D)  Undetectable immune response in the presence of antigens 
A)  Disturbance in the immunologic tolerance of self-antigens 
B)  Immunologic reaction of one person to the tissue of another person 
C)  Altered immunologic response to an antigen that results in disease 
D)  Undetectable immune response in the presence of antigens

Question 13

During an IgE-mediated hypersensitivity reaction,what causes bronchospasm?

Accepted Answer

A)  Bronchial edema caused by the chemotactic factor of anaphylaxis 
B)  Bronchial edema caused by binding of the cytotropic antibody 
C)  Smooth muscle contraction caused by histamine bound to H₁ receptors 
D)  Smooth muscle contraction caused by histamine bound to H₂ receptors 
A)  Bronchial edema caused by the chemotactic factor of anaphylaxis 
B)  Bronchial edema caused by binding of the cytotropic antibody 
C)  Smooth muscle contraction caused by histamine bound to H₁ receptors 
D)  Smooth muscle contraction caused by histamine bound to H₂ receptors

Question 14

How are target cells destroyed in a type II hypersensitivity reaction?

Accepted Answer

A)  Complement-mediated cell lysis 
B)  Phagocytosis by macrophages 
C)  Neutrophil granules and toxic oxygen products 
D)  Natural killer cells 
A)  Complement-mediated cell lysis 
B)  Phagocytosis by macrophages 
C)  Neutrophil granules and toxic oxygen products 
D)  Natural killer cells

Question 15

Graves disease (hyperthyroidism)is an example of which type II hypersensitivity reaction?

Accepted Answer

A)  Modulation 
B)  Antibody-dependent cell-mediated cytotoxicity 
C)  Neutrophil-mediated damage 
D)  Complement-mediated lysis 
A)  Modulation 
B)  Antibody-dependent cell-mediated cytotoxicity 
C)  Neutrophil-mediated damage 
D)  Complement-mediated lysis

Question 16

During an IgE-mediated hypersensitivity reaction,which leukocyte is activated?

Accepted Answer

A)  Neutrophils 
B)  Monocytes 
C)  Eosinophils 
D)  T lymphocytes 
A)  Neutrophils 
B)  Monocytes 
C)  Eosinophils 
D)  T lymphocytes

Question 17

Which disorders are considered autoimmune? (Select all that apply.)

Accepted Answer

A)  Crohn disease 
B)  Addison disease 
C)  Rheumatoid arthritis 
D)  Systemic lupus erythematosus 
E)  Noninsulin-dependent diabetes 
A)  Crohn disease 
B)  Addison disease 
C)  Rheumatoid arthritis 
D)  Systemic lupus erythematosus 
E)  Noninsulin-dependent diabetes

Question 18

Urticaria are a manifestation of a which type of hypersensitivity reaction?

Accepted Answer

A)  IV 
B)  III 
C)  II 
D)  I 
A)  IV 
B)  III 
C)  II 
D)  I

Question 19

Graves disease is a result of:

Accepted Answer

A)  Increased levels of circulating immunoglobulins 
B)  The infiltration of the thyroid with T lymphocytes 
C)  Autoantibodies binding to thyroid-stimulating hormone (TSH)-receptor sites 
D)  Exposure to acetylates in substances such as rubber 
A)  Increased levels of circulating immunoglobulins 
B)  The infiltration of the thyroid with T lymphocytes 
C)  Autoantibodies binding to thyroid-stimulating hormone (TSH)-receptor sites 
D)  Exposure to acetylates in substances such as rubber

Question 20

What characteristic do atopic individuals have that make them genetically predisposed to develop allergies?

Accepted Answer

A)  Greater quantities of histamine 
B)  More histamine receptors 
C)  Greater quantities of IgE 
D)  A deficiency in epinephrine 
A)  Greater quantities of histamine 
B)  More histamine receptors 
C)  Greater quantities of IgE 
D)  A deficiency in epinephrine

Exam 9: Alterations in Immunity and Inflammation

Immunoglobulin E (IgE)is associated with which type of hypersensitivity reaction?

Exposure to which of the following could result in a type IV hypersensitivity reaction? (Select all that apply.)

In which primary immune deficiency is there a partial-to-complete absence of T-cell immunity?

When soluble antigens from infectious agents enter circulation,tissue damage is a result of:

A type IV hypersensitivity reaction causes which result?

A person with type O blood is likely to have high titers of which anti-antibodies?

Which statement is true concerning an atopic individual?

When a tuberculin skin test is positive,the hard center and erythema surrounding the induration are a result of which of the following? (Select all that apply.)

Which class of immunoglobulins forms isohemagglutinins?

Which component of the immune system is deficient in individuals with infections caused by viruses,fungi,or yeast?

Considering the effects of nutritional deficiencies on the immune system,severe deficits in calories and protein lead to deficiencies in the formation of which immune cells?

Hypersensitivity is best defined as a(an):

During an IgE-mediated hypersensitivity reaction,what causes bronchospasm?

How are target cells destroyed in a type II hypersensitivity reaction?

Graves disease (hyperthyroidism)is an example of which type II hypersensitivity reaction?

During an IgE-mediated hypersensitivity reaction,which leukocyte is activated?

Which disorders are considered autoimmune? (Select all that apply.)

Urticaria are a manifestation of a which type of hypersensitivity reaction?

Graves disease is a result of:

What characteristic do atopic individuals have that make them genetically predisposed to develop allergies?

Cellular Biology

Altered Cellular and Tissue Biology

The Cellular Environment: Fluids and Electrolytes, Acids and Bases

Genes and Genetic Diseases

Genes, Environment-Lifestyle, and Common Diseases

Epigenetics and Disease

Innate Immunity: Inflammation

Adaptive Immunity

Infection

Stress and Disease

Cancer Biology

Cancer Epidemiology

Cancer in Children

Structure and Function of the Neurologic System

Pain, Temperature Regulation, Sleep, and Sensory Function

Alterations in Cognitive Systems,Cerebral Hemodynamics,and Motor Function

Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction

Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

Alterations of Neurologic Function in Children

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

Structure and Function of the Reproductive Systems

Alterations of the Female Reproductive System

Alterations of the Male Reproductive System

Sexually Transmitted Infections

Structure and Function of the Hematologic System

Alterations of Erythrocyte Function

Alterations of Leukocyte, Lymphoid, and Hemostatic Function

Alterations of Hematologic Function in Children

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Alterations of Pulmonary Function in Children

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function

Alterations of Musculoskeletal Function in Children

Structure, Function, and Disorders of the Integument

Alterations of the Integument in Children

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children

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