Question 1

What is the name of the disorder in which levels of bilirubin remain excessively high in the newborn and are deposited in the brain?

Accepted Answer

A) Kernicterus 
B) Icterus neonatorum 
C) Jaundice 
D) Icterus gravis neonatorum 
A) Kernicterus 
B) Icterus neonatorum 
C) Jaundice 
D) Icterus gravis neonatorum

Question 2

A patient has primary immune thrombocytopenic purpura (ITP) and is hospitalized after a bleeding episode. What treatment does the healthcare provider anticipate being ordered for this patient?

Accepted Answer

A) Blood transfusions 
B) Infusion of IVIG 
C) Anticoagulants 
D) Large doses of folic acid 
A) Blood transfusions 
B) Infusion of IVIG 
C) Anticoagulants 
D) Large doses of folic acid

Question 3

What are the common triggers for sickle cell crisis? (Select all that apply.)

Accepted Answer

A) Fever 
B) Infection 
C) Dehydration 
D) Alkalosis 
E) Exposure to the cold 
A) Fever 
B) Infection 
C) Dehydration 
D) Alkalosis 
E) Exposure to the cold

Question 4

A patient has microcytic, hypochromic anemia. Which type of treatment or procedure does the healthcare professional discuss as a potential cure with the patient?

Accepted Answer

A) Cord blood transplantation 
B) Scheduled infusion of gamma globulins 
C) Massive blood transfusions 
D) Repeated injections of Rho-GAM 
A) Cord blood transplantation 
B) Scheduled infusion of gamma globulins 
C) Massive blood transfusions 
D) Repeated injections of Rho-GAM

Question 5

What is the cause of polycythemia in the fetus?

Accepted Answer

A) Fetal hemoglobin has a greater affinity for oxygen as a result of diphosphoglycerate (DPG). 
B) The fetus has a different hemoglobin structure of two a- and two g-chains rather than two a-and two b-chains. 
C) Increased erythropoiesis occurs in response to the hypoxic intrauterine environment. 
D) The lungs of the fetus are undeveloped and unable to diffuse oxygen adequately to the pulmonary capillaries. 
A) Fetal hemoglobin has a greater affinity for oxygen as a result of diphosphoglycerate (DPG). 
B) The fetus has a different hemoglobin structure of two a- and two g-chains rather than two a-and two b-chains. 
C) Increased erythropoiesis occurs in response to the hypoxic intrauterine environment. 
D) The lungs of the fetus are undeveloped and unable to diffuse oxygen adequately to the pulmonary capillaries.

Question 6

An infant was born with hemolytic disease of the fetus and newborn (HDFN). What treatment does the healthcare professional anticipate for this baby?

Accepted Answer

A) Administration of intravenous fluids to dilute the blood 
B) Replacement transfusion of Rh-positive blood not contaminated with anti-Rh antibodies 
C) Performance of a splenectomy to prevent the destruction of abnormal erythrocytes 
D) Replacement transfusion of Rh-negative erythrocytes 
A) Administration of intravenous fluids to dilute the blood 
B) Replacement transfusion of Rh-positive blood not contaminated with anti-Rh antibodies 
C) Performance of a splenectomy to prevent the destruction of abnormal erythrocytes 
D) Replacement transfusion of Rh-negative erythrocytes

Question 7

When diagnosed with hemolytic disease of the fetus and newborn (HDFN), why does the newborn develop hyperbilirubinemia after birth but not in utero?

Accepted Answer

A) Excretion of unconjugated bilirubin through the placenta into the mother's circulation is no longer possible. 
B) Hemoglobin does not breakdown into bilirubin in the intrauterine environment. 
C) The liver of the fetus is too immature to conjugate bilirubin from a lipid-soluble to water-soluble form. 
D) The destruction of erythrocytes producing bilirubin is greater after birth. 
A) Excretion of unconjugated bilirubin through the placenta into the mother's circulation is no longer possible. 
B) Hemoglobin does not breakdown into bilirubin in the intrauterine environment. 
C) The liver of the fetus is too immature to conjugate bilirubin from a lipid-soluble to water-soluble form. 
D) The destruction of erythrocytes producing bilirubin is greater after birth.

Question 8

The healthcare professional explains to a student that glucose 6-phosphate dehydrogenase (G6PD) deficiency is what type of inherited disorder?

Accepted Answer

A) X-linked dominant 
B) X-linked recessive 
C) Autosomal dominant 
D) Autosomal recessive 
A) X-linked dominant 
B) X-linked recessive 
C) Autosomal dominant 
D) Autosomal recessive

Question 9

The alpha- and beta-thalassemias are considered what types of inherited disorder?

Accepted Answer

A) Autosomal recessive 
B) Autosomal dominant 
C) X-linked recessive 
D) X-linked dominant 
A) Autosomal recessive 
B) Autosomal dominant 
C) X-linked recessive 
D) X-linked dominant

Question 10

A child has iron deficiency anemia. In addition to iron supplements, what else does the healthcare professional educate the parents on giving the child?

Accepted Answer

A) Vitamin A 
B) Magnesium 
C) Vitamin C 
D) Zinc 
A) Vitamin A 
B) Magnesium 
C) Vitamin C 
D) Zinc

Question 11

What is the most common cause of insufficient erythropoiesis in children?

Accepted Answer

A) Folic acid deficiency 
B) Iron deficiency 
C) Hemoglobin abnormality 
D) Erythrocyte abnormality 
A) Folic acid deficiency 
B) Iron deficiency 
C) Hemoglobin abnormality 
D) Erythrocyte abnormality

Question 12

Which mother does the healthcare professional prepare to administer Rh immune globulin (Rho-GAM) to?

Accepted Answer

A) Is Rh-positive and the fetus is Rh-negative 
B) Is Rh-negative and the fetus is Rh-positive 
C) Has type A blood and the fetus has type O 
D) Has type AB blood and the fetus has type B 
A) Is Rh-positive and the fetus is Rh-negative 
B) Is Rh-negative and the fetus is Rh-positive 
C) Has type A blood and the fetus has type O 
D) Has type AB blood and the fetus has type B

Exam 31: Alterations of Hematologic Function in Children

What is the name of the disorder in which levels of bilirubin remain excessively high in the newborn and are deposited in the brain?

A patient has primary immune thrombocytopenic purpura (ITP) and is hospitalized after a bleeding episode. What treatment does the healthcare provider anticipate being ordered for this patient?

What are the common triggers for sickle cell crisis? (Select all that apply.)

A patient has microcytic, hypochromic anemia. Which type of treatment or procedure does the healthcare professional discuss as a potential cure with the patient?

What is the cause of polycythemia in the fetus?

An infant was born with hemolytic disease of the fetus and newborn (HDFN). What treatment does the healthcare professional anticipate for this baby?

When diagnosed with hemolytic disease of the fetus and newborn (HDFN), why does the newborn develop hyperbilirubinemia after birth but not in utero?

The healthcare professional explains to a student that glucose 6-phosphate dehydrogenase (G6PD) deficiency is what type of inherited disorder?

The alpha- and beta-thalassemias are considered what types of inherited disorder?

A child has iron deficiency anemia. In addition to iron supplements, what else does the healthcare professional educate the parents on giving the child?

What is the most common cause of insufficient erythropoiesis in children?

Which mother does the healthcare professional prepare to administer Rh immune globulin (Rho-GAM) to?

Cellular Biology

Altered Cellular and Tissue Biology: Environmental Agents

The Cellular Environment: Fluids and Electrolytes, Acids and Bases

Genes and Genetic Diseases

Genes, Environment-Lifestyle, and Common Diseases

Epigenetics and Disease

Innate Immunity: Inflammation and Wound Healing

Adaptive Immunity

Alterations in Immunity and Inflammation

Infection

Stress and Disease

Cancer Biology

Cancer Epidemiology

Cancer in Children

Structure and Function of the Neurologic System

Pain, Temperature Regulation, Sleep, and Sensory Function

Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function

Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction

Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

Alterations of Neurologic Function in Children

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

Obesity and Disorders of Nutrition

Structure and Function of the Reproductive Systems

Alterations of the Female Reproductive System

Alterations of the Male Reproductive System

Sexually Transmitted Infections

Structure and Function of the Hematologic System

Alterations of Erythrocytes, Platelets, and Hemostatic Function

Alterations of Leukocyte and Lymphoid Function

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Alterations of Pulmonary Function in Children

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function

Alterations of Musculoskeletal Function in Children

Structure, Function, and Disorders of the Integument

Alterations of the Integument in Children

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children

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