Exam 31: Alterations of Hematologic Function in Children

A patient has leukemia. The healthcare professional explains to a patient about the significance of hyperdiploidy. What statement by the professional is most accurate?

Which blood cell type is elevated at birth and through the preschool years, but decreases to adult levels afterward?

How is erythroblastosis fetalis defined?

How does hemolytic disease of the fetus and newborn (HDFN) cause acquired congenital hemolytic anemia?

Which manifestations of vasoocclusive crisis are associated with sickle cell disease (SCD) in children?

A student asks the professor why hemophilia A is seen mostly in men. The professor explains that hemophilia A is considered to be what type of inherited disorder?

A couple who both carry the sickle cell trait wish to have children. What does the healthcare professional tell them is the chance that each pregnancy will result in a child who has sickle cell disease (SCD)?

A newborn displays pallor, tachycardia, and has a systolic murmur. What hemoglobin value does the healthcare professional correlate with these manifestations?

Hemophilia B is caused by a deficiency of which clotting factor?

When does fetal erythrocyte production shift from the liver to the bone marrow?

A patient has thalassemia major. After receiving multiple blood transfusions over the last several months, what complication does the healthcare professional assess the patient for?

Which disease is an autosomal dominant inherited hemorrhagic disease?

The healthcare professional is caring for a woman whose baby died of hydrops fetalis. How does the professional explain this condition to a student?

A pediatric patient presents with pallor, fatigue, fever, petechiae, and purpura. What diagnostic testing does the healthcare professional help prepare the patient for? (Select all that apply.)

A child has sickle cell disease (SCD). What treatment or therapy does the healthcare professional discuss with the parents and child?

A healthcare professional is teaching a community group about inherited disorders. What pattern of inheritance does the professional describe for sickle cell disease?

A healthcare professional educates parents to monitor their child's dietary intake for sufficient iron during which period of time as the priority?

In a full-term infant, the normal erythrocyte life span is _____ days.

Why does fetal hemoglobin have a greater affinity for oxygen than adult hemoglobin?

Hemoglobin S (HbS) is formed in sickle cell disease as a result of which process?