Question 1

Embryonic tumors are usually diagnosed after 5 years of age.

Accepted Answer

A) True 
 B)False  False

Question 2

Children with acquired immunodeficiency syndrome (AIDS) have an increased risk of developing certain cancers such as Kaposi sarcoma.

Accepted Answer

A) True 
 B)False  True

Question 3

What congenital malformation is commonly linked to acute leukemia in children?

Accepted Answer

A) Down syndrome 
B) Wilms tumor 
C) Retinoblastoma 
D) Neuroblastoma 
A) Down syndrome 
B) Wilms tumor 
C) Retinoblastoma 
D) Neuroblastoma A

Question 4

Secondary cancers are a late effect faced by children cured of cancer.

Accepted Answer

A) True 
 B)False

Question 5

When are childhood cancers most often diagnosed?

Accepted Answer

A) During infancy 
B) At peak times of physical growth 
C) After diagnosis of chronic illness 
D) After an acute illness 
A) During infancy 
B) At peak times of physical growth 
C) After diagnosis of chronic illness 
D) After an acute illness

Question 6

Chronic myelogenous leukemia, retinoblastoma, and osteosarcoma are associated with which genetic factors in childhood cancers?

Accepted Answer

A) Chromosome aberrations or single gene defects 
B) Mutation of proto-oncogenes to oncogenes 
C) Tumor-suppressor genes that have lost their suppressor function 
D) Congenital malformations 
A) Chromosome aberrations or single gene defects 
B) Mutation of proto-oncogenes to oncogenes 
C) Tumor-suppressor genes that have lost their suppressor function 
D) Congenital malformations

Question 7

Cancer is the leading cause of death in children.

Accepted Answer

A) True 
 B)False

Question 8

Most childhood cancers arise from the:

Accepted Answer

A) epithelium. 
B) mesodermal germ layer. 
C) embryologic ectodermal layer. 
D) viscera. 
A) epithelium. 
B) mesodermal germ layer. 
C) embryologic ectodermal layer. 
D) viscera.

Question 9

There are research data to support a carcinogenic relationship in children resulting from exposure to the _____ virus.

Accepted Answer

A) herpes simplex 
B) influenza 
C) varicella 
D) Epstein-Barr 
A) herpes simplex 
B) influenza 
C) varicella 
D) Epstein-Barr

Question 10

Leukemia is the most common malignancy in children.

Accepted Answer

A) True 
 B)False

Question 11

Mutation of proto-oncogenes into oncogenes stimulates uncontrolled cell growth.

Accepted Answer

A) True 
 B)False

Question 12

Cancers in children are slow growing and usually have not metastasized at time of diagnosis.

Accepted Answer

A) True 
 B)False

Question 13

Childhood exposure to all of the following risk factors increases susceptibility to cancer except:

Accepted Answer

A) drugs. 
B) ionizing radiation. 
C) cigarette smoke. 
D) viruses. 
A) drugs. 
B) ionizing radiation. 
C) cigarette smoke. 
D) viruses.

Question 14

Most childhood cancers originate from the mesodermal germ layer that gives rise to connective tissue, bone, blood, blood vessels, kidney, and lymph.

Accepted Answer

A) True 
 B)False

Question 15

Prenatal exposure to diethylstilbestrol (DES) can result in:

Accepted Answer

A) breast cancer. 
B) leukemia. 
C) vaginal cancer. 
D) lymphoma. 
A) breast cancer. 
B) leukemia. 
C) vaginal cancer. 
D) lymphoma.

Question 16

Mutations of proto-oncogenes into oncogenes have been identified with pediatric lymphoma and leukemia.

Accepted Answer

A) True 
 B)False

Question 17

What percentage of children with cancer can be cured?

Accepted Answer

A) 40% 
B) 50% 
C) 60% 
D) 70% 
A) 40% 
B) 50% 
C) 60% 
D) 70%

Exam 13: Cancer in Children

Embryonic tumors are usually diagnosed after 5 years of age.

Children with acquired immunodeficiency syndrome (AIDS) have an increased risk of developing certain cancers such as Kaposi sarcoma.

What congenital malformation is commonly linked to acute leukemia in children?

Secondary cancers are a late effect faced by children cured of cancer.

When are childhood cancers most often diagnosed?

Chronic myelogenous leukemia, retinoblastoma, and osteosarcoma are associated with which genetic factors in childhood cancers?

Cancer is the leading cause of death in children.

Most childhood cancers arise from the:

There are research data to support a carcinogenic relationship in children resulting from exposure to the _____ virus.

Leukemia is the most common malignancy in children.

Mutation of proto-oncogenes into oncogenes stimulates uncontrolled cell growth.

Cancers in children are slow growing and usually have not metastasized at time of diagnosis.

Childhood exposure to all of the following risk factors increases susceptibility to cancer except:

Most childhood cancers originate from the mesodermal germ layer that gives rise to connective tissue, bone, blood, blood vessels, kidney, and lymph.

Prenatal exposure to diethylstilbestrol (DES) can result in:

Mutations of proto-oncogenes into oncogenes have been identified with pediatric lymphoma and leukemia.

What percentage of children with cancer can be cured?

Cellular Biology

Altered Cellular and Tissue Biology

The Cellular Environment: Fluids and Electrolytes, Acids and Bases

Genes and Genetic Diseases

Genes, Environment, and Common Diseases

Innate Immunity: Inflammation

Adaptive Immunity

Alterations in Immunity and Inflammation

Infection

Stress and Disease

Biology, Clinical Manifestations, and Treatment of Cancer

Cancer Epidemiology

Structure and Function of the Neurologic System

Pain, Temperature Regulation, Sleep, and Sensory Function

Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function

Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction

Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

Alterations of Neurologic Function in Children

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

Structure and Function of the Reproductive System

Alterations of the Reproductive Systems

Sexually Transmitted Infections

Structure and Function of the Hematologic System

Alterations of Erythrocyte Function

Alterations of Leukocyte, Lymphoid, and Hemostatic Function

Alterations of Hematologic Function in Children

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Alterations of Pulmonary Function in Children

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function

Alterations of Musculoskeletal Function in Children

Structure, Function, and Disorders of the Integument

Alterations of the Integument in Children

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adult

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children

Filters