Exam 14: Dna and the Gene: Synthesis and Repair

Bodnar et al.(1998)used telomerase to extend the life span of normal human cells.Telomere shortening puts a limit on the number of times a cell can divide.How might adding telomerase affect cellular aging?

DNA is synthesized through a process known as

The fact that within a double-stranded DNA molecule,adenine forms two hydrogen bonds with thymine and cytosine forms three hydrogen bonds with guanine is known as

Watson and Crick elucidated the structure of DNA in 1953.Their research built on and helped explain the findings of other scientists,including

In the mismatch repair process,enzyme complexes replace bases that were incorrectly inserted into the newly synthesized DNA strand.To function,they must be able to distinguish between the parent DNA strand and the new strand.How is this accomplished?

What provides the energy for the polymerization reactions in DNA synthesis?

Who performed the classic experiments that proved DNA was copied by semiconservative replication?

Which of the following cells do not have active telomerase activity?

Figure 14.3 -Refer to Figure 14.3.Which of the structures in the figure breaks hydrogen bonds between complementary bases?

The transduction experiments done by Hershey and Chase,and the transformation experiments done by Griffith,supported the same conclusion,which was that

Which of the following agents can cause mutations in DNA?

Figure 14.1 -Refer to Figure 14.1.What bases will be added to the primer as DNA replication proceeds? The bases should appear in the order that they will be added.

-Where would Okazaki fragments be found in the image above? Note: The black boxes represent RNA primers and the polarities of the template strands are indicated. A)A,B B)C,D C)A,C D)B,D E)A,D

Figure 14.2 -In Figure 14.2,which is the template strand?

Hershey and Chase set out to determine what molecule served as the unit of inheritance.They completed a series of transduction experiments in which E.coli was infected by a T2 virus.Which molecular component of the T2 virus actually ended up inside the cell?

What are pyrimidine dimers?

What is a major difference between eukaryotic DNA replication and prokaryotic DNA replication?

Which of the following are important in reducing the errors in DNA replication in E.coli organisms?

How does the simple primary and secondary structure of DNA hold the information needed to code for the many features of multicellular organisms?

Telomere shortening is a problem in which types of cells?